Lecture 1 Flashcards
Last universal common ancestor
LUCA
Hypothesis about LUCA
- Existed about 4 billion years ago
- Last common ancestor of all cellular life which exists on earth today
- After billion of years of evolution LUCA diverged into the different forms of life through natural selection
What we see today is the result of…
Evolution
Domain Bacteria
Most diverse and widespread prokaryotes. Have rod shaped structures
Domain Archaea
Live in Earth’s extreme environments such as hot springs. Have round structures
Domain Eukarya
Kingdom Plantae: Consists of terrestrial multicellular eukaryotes that carry out photosynthesis
Kingdom Fungi: Absorb nutrients from outside their bodies
Kingdom Animalia: Consists of multicellular eukaryotes that ingest other organisms
Protists: Unicellular eukaryotes
Polytomy
A branch point leading to multiple lineages
Horizontal Gene Transfer
movement of genetic material between organisms in a way that is not through traditional inheritance (i.e., not from parent to offspring). It occurs across species, and even across domains of life, and is an important mechanism in evolution
Organisms adapted to various habitats on earth via
Evolution
Why study the diversity of life?
Humans are inherently interested in our environment
Humans are inherently interested in ourselves
Taxas and classification of humans
Domain: Eukaryota
Kingdom: Animalia
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
Taxonomy
Study organisms, name them and put them into similar groups
Phylogeny
deduce evolutionary relationship between organisms put similar groups
Naming is important to
communicate unambiguously. For example the cougar is also known as panther, mountain lion but its overall binomial name is Puma concolor
Conservation ecology
- Organisms are constantly interacting with environment and one another
- Cannot intervene with the system without knowing these interactions
- Predator and prey: Changes in population sizes of predator and prey are known to synchronize
Ex: Snowshoe hare vs canada lynx
Conversation ecology with woodland caribou
Commercial foresting: logging, building roads, pipelines etc
Caribous can not sustain population when the old forest is too disrupted
Parasites
Organisms thrive by parasitizing on their host, many infect humans - need to know what they are to effectively combat them
Mycobacterium tuberculosis
Bacteria
Causative agent of tuberculosis
HIV
Human immunodeficiency virus (HIV)
Causative agent of AIDS
Staphylococcus aureus
Bacteria
Causative agent of various skin and respiratory infections
Monkeypox virus
Causative agent of Mpox
Epidemics vs pandemics
It is natural for a population to be affected by various health detriments (such as diseases)
Epidemic: Significant rise in occurrence of a disease above the rate which is normally expected in a local population
Pandemic: Global epidemic usually on more than one continent
COVID 19 pandemic
Early 2020 - caused by coronavirus
SARS - CoV-2 is the name of the virus: Severe acute respiratory syndrome coronavirus 2
Covid 19 is the symptom caused by the virus
Describe physical appearance of covid 19 virus
Spike protein sticks out of the envelope making the virus look like a ‘sun’ (corona)
How many different human host coronavirus are there
7 different: 4 are not as problematic cause 15% of common cold and have been recognized since 1960
SARS - CoV - 1
- Severe Acute Respiratory Syndrome Coronavirus 1
- causative agent of 2002 – 2004 SARS epidemic
- about 8000 documented cases (0.08 million) across 29 countries
- 10% fatality rate
MERS-CoV
Middle East Respiratory Syndrome Coronavirus
* first reported in 2012, and have caused multiple outbreaks since then
* about 2500 cases (0.025 million) documented until July 2022 across ~30 countries
* up to 35% fatality late
SARS-CoV-2
- Causative agent of COVID-19
- about 612 million cases as of September 2022, globally
- 6.5 million deaths, about 1% fatality rate
- tremendous damage to human society
Prior to covid 19 we already have
- Recognized, identified and studied multiple coronaviruses
- Encountered epidemic(s) caused by more deadlier versions of coronavirus
- Experience combatting this infection
- …in addition to knowledge on other viruses, vaccination, epidemiology, etc