Lecture 1 Flashcards
Less than 6 congenitally missing teeth:
hypodontia
More than 6 congenitally missing teeth:
oligodontia
Abscence of all teeth:
anodontia
Extra teeth (supernumerary teeth):
hyperdontia
What 7 things are known to result in congenitally missing teeth?
- ectodermal dysplasia
- hypothyroidism
- down syndrome
- cleft palate
- genetics
- radiation
- random
Group of syndromes causing missing or peg shaped teeth, thin, sparse hair, and absence of sweat glands:
ectodermal dysplasia
Cleft palates occur in _____ briths
600-800
What is the cause of congenitally missing teeth?
due to disturbances during the initial stages of tooth formation (initiation & proliferation)
What specific stages of tooth formation are disturbed resulting in congenitally missing teeth?
initiation & proliferation
T/F: If a primary tooth is missing, there is a chance the permanent successor will be present
false- since primary tooth buds give rise to permanent tooth buds, it is not possible to be a successor if the primary tooth bud is missing
Is it possible to have missing permanent teeth even when there was a primary tooth?
yes
What is the INCIDENCE of hypodontia of in the general population?
General population: 2-10% (excluding 3rd molars)
What is the incidence of congenitally missing primary teeth?
0.1-0.4%
What is the incidence of congenitally missing 3rd molars?
20-25%
What sex is hypodontia more common in?
females (3:2 ratio)
T/F: Hypodontia commonly runs in families
true
What is the general rule to hypodontia?
As a general rule, if only one or a few teeth are missing, the absent tooth will be the most DISTAL tooth of any given type
Missing teeth can be inherited as part of a syndrome or a:
polygenic multifactorial model of etiology
What genes are etiologic factor in hypodontia?
MSX1, PAX9, AXIN2
List 2 medically induced etiologies of hypodontia:
- cytotoxic drugs
- radiotherapy
T/F: The etiology of hypodontia can be random
true
What are the most commonly missing permanent teeth?
mandibular 2nd premolars
maxillary 2nd premolars
maxillary lateral incisors
maxillary second molars