Lecture 1 Flashcards

1
Q

Total Body Water?

A

(Body Fluids)
-Varies from 50-70% of body weight
-Average person is about 42 kg or 42 L

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2
Q

(Percentage of Water in Tissues)
Skin?

A

-72% of water
-18% of body weight
-9.1 L of water

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3
Q

(Percentage of Water in Tissues)
Muscle?

A

-76% of water
-41.7% of body weight
-22.1 L of water

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4
Q

Tissues that make up most of body H2O?

A

Skin and Muscle

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5
Q

Which Tissue is susceptible to edema?

A

Brain

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6
Q

Which Tissue is the least because of hydrophobicity?

A

Adipose Tissue

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7
Q

Intracellular (ICF)?

A

-40% of body weight
-28 L

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8
Q

Extracellular (ECF)?

A

-20% of body weight
-14 L

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9
Q

Plasma?

A

-4-5% of body weight
-25% of ECF

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10
Q

Interstitial?

A

-75% of ECF

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11
Q

What makes up the ECF?

A

Interstitial + Plasma

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12
Q

2/3 of TBW?

A

ICF

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13
Q

1/3 of TBW?

A

ECF

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14
Q

What can pass through cell membrane?

A

Only water

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15
Q

What wall is very permeable?

A

Capillary Wall

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16
Q

ECF + ICF = ?

A

TBW

17
Q

(Measuring the Size of Compartments)
TBW?

A

(Radio-Labeled H2O)
HTO and D2O

18
Q

(Measuring the Size of Compartments)
ECF?

A

-Inulin (only in ECF)
-Radio-sodium

19
Q

(Measuring the Size of Compartments)
Plasma?

A

-I-albumin
-Evans Blue

20
Q

(Measuring the Size of Compartments)
Blood?

A

Cr-RBCs

21
Q

(Measuring the Size of Compartments)
Interstitial?

A

-Indirect
-(ECF - Plasma)

22
Q

(Measuring the Size of Compartments)
ICF?

A

-Indirect
-(TBW - ECF)

23
Q

Standard Equation?

A

Compartment Volume = (Amount Injected) / (Final Concentration)

24
Q

Molar Concentration?

A

(# of atoms or charge of ion) x (mmol/L)

25
Q

Plasma Electrolyte Total?

A

300 mOsmoles/L of H2O

26
Q

Osmolality?

A

millimoles of solute/kg of H2O

27
Q

Osmolarity?

A

millimoles of solute/L of H2O

28
Q

Activity of H2O decreases as?

A

Osmolality increases

29
Q

Colligative Properties of Solutions depend on?

A

Number of molecules and not their nature
-Boiling Point
-Freezing Point
-Vapor Pressure
-Osmotic Pressure

30
Q

Decrease due to lots of protons (because HCl)?

A

Vomiting

31
Q

Decrease due to lots of bicarb?

A

Diarrhea

32
Q

(Daily Turnover of Fluids)
Infant?

A

-2.3 L of TBW (77%)
-16 (1/6)

33
Q

(Daily Turnover of Fluids)
Adult?

A

-42 L of TBW (60%)
-6 (1/16)

34
Q

Na primarily in?

A

Areas after the stomach

35
Q

Cl primarily in?

A

Saliva and Gastric Juices

36
Q

ECF cation is?

A

Na

37
Q

ECF anion is?

A

Cl- (and HCO3-)

38
Q

ICF cation is?

A

K+

39
Q

ICF buffer is?

A

H2PO4-