lect26-Reg of Respiration Flashcards

1
Q

what does the dorsal respiratory group do

A

sets basic rhythm of respiration
prinicipal initiator of phrenic nerve activity
receive many fibers from VRG
receives lots of sensory info via the nucleus tracts solitaries
mainly associated with inspiration: ESTABLISHES RAMP SIGNAL

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2
Q

what is the NTS

A

sensory termination of both the vagal and glossopharyngeal nerves in the DRG and receives info from peripheral chemoreceptors, baroreceptors, and several receptors in the lungs

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3
Q

what is the primary function of the PRG

A

control the switch off point of the inspiratory ramp

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4
Q

what do lesions of the PRG result in

A

loss of the ability to turn off the inspiration without additional input from vagus nerves

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5
Q

what does the PRG mainly do

A

controls rate and depth of breathing

transmits signals to the inspiratory center

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6
Q

what happens when there is a loss of function in the apneustic center

A

causes prolonged inspiratory gasping

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7
Q

what is the normal function of the apneustic center

A

limit lung expansion

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8
Q

define apneusis

A

failure to turn off inspiration

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9
Q

what is the botzinger complex associated with

A

coordinating VRG output

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10
Q

what is the intermediate part of VRG associated with

A

dilation of the upper airway during inspiration

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11
Q

describe pre-botzinger complex

A

site which generates the timing (frequency) of the respiratory rhythm (central pattern generator
decides length of inspiration and expiration and also determines frequency

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12
Q

define hering-breuer inflation reflex

A

protective mechanism to prevent excess inflation of the lungs

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13
Q

what do chemoreceptors do when hypoxia or hypercapnia occur

A

rate of activity increases

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14
Q

what are central chemoreceptors sensitive to

A

indirectly to CO2 levels (H+) based on pH

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15
Q

what are peripheral chemoreceptors sensitive to

A

oxygen

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16
Q

what are examples of peripheral chemoreceptors

A

receptors in aortic arch

carotid body receptors

17
Q

describe type 1 (glomus) cells of carotid bodies

A

chemosensors

effected by PO2 (K+ channels open when high and close when low)

18
Q

describe type 2 (sustentacullar cells)

A

play a support role similar to glial cells

19
Q

what PO2 are chemoreceptors exposed to

A

PO2 of arterial blood not venous

20
Q

how do signals from slow-adapting pulm stretch receptors travel and what do they do

A

in vagus nerve to medulla

terminate inspiration and prolong expiration

21
Q

what do rapidly-adapting pulm stretch receptors sign

A

signals travel in vagus nerve to brain and elicit cough (override normal respiratory control mechanisms)

22
Q

what do J receptors do

A

sensitive to pulmonary edema
signals travel from these receptors to brain via vagus nerve and stimulate cough and tachypnea (override normal respiratory control mechanisms)

23
Q

define hyperpnea

A

increasingly deeper and rapid breathing