lect-22 Pulmonary ventilation Flashcards

1
Q

what is respiratory epithelium

A

pseudo stratified ciliated columnar epithelium with goblet cells

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2
Q

what type of cartilage rings are in the trachea

A

incomplete cartilaginous rings

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3
Q

where are the carina located and what are they sensitive to

A

inside trachea at point of branching of primary bronchi
sensitive to irruption
produces cough reflex

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4
Q

what do the primary bronchi supply to

A

lungs

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5
Q

what do the secondary bronchi supply

A

lobes

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6
Q

what do the tertiary bronchi supply

A

lobules

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7
Q

what type of cartilage is in bronchioles

A

NONE

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8
Q

where is the first place in the respiratory tree that you can get gas exchange

A

respiratory branches of bronchioles

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9
Q

what respiratory muscles are inspiratory

A
respiratory diaphragm
external intercostal muscles (limited)
sternomastoids
serratus anterior muscles
scalene muscles
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10
Q

what muscles are form forceful expiration

A

abdominal muscles

internal intercostals

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11
Q

define total lung capacity

A

maximum volume of gas the lungs can hold

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12
Q

define volumes

A

distinct, non-overlapping sub-compartments referred to as lung volumes

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13
Q

define tidal volume

A

500 ml

volume of air that is inspired or expired with each breath at rest

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14
Q

define inspiratory reserve volume

A

3000 ml

volume of air that can be inspired in addition to tidal volume with forceful inspiration

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15
Q

define expiratory reserve volume

A

1100ml

additional volume of air that can be expired at end of tidal volume by forceful expiration

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16
Q

define residual volume

A

1200 ml

volume of air remaining in lungs after forceful expiration

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17
Q

define vital capacity

A

4600 ml
sum of all the volumes that can be inspired or exhaled
inspiration to the max extent plus expiration to the max extent

18
Q

define total lung capacity

A

5800 ml

the sum of all the volumes= vital capacity plus residual volume

19
Q

define inspiratory capacity

A

3500 ml

the sum of volumes above resting capacity= tidal volume plus inspiratory reserve volume

20
Q

define functional residual capacity

A

2300 ml

the sum of volumes below resting capacity= expiratory reserve volume + residual volume

21
Q

define minute ventilation

A

total volume of gases moved into or out of the lungs per minute

22
Q

define alveolar ventilation

A

total volume of gases that enter spaces participating in gas exchange per minute

23
Q

what is found in the anatomical dead space

A

trachea, bronchi, bronchioles

24
Q

what is found in the physiological dead space

A

anatomical dead space + ventilated alveoli with poor or absent perfusion

25
what is the total dead space in a normal person
0.15 liters
26
what is the normal tidal volume
0.35 liters
27
what does the amount of CO2 in regions of lungs involved in gas exchange equal
that of arterial blood
28
define pleural pressure
pressure of the fluid between parietal pleura and the visceral pleura
29
define alveolar pressure
pressure of the air inside of the alveoli
30
define transpulmonary pressure
difference between the alveolar pressure and the pleural pressure
31
how is pleural pressure measured
measured in centimeters of water
32
what is pleural pressure during inspiration and expiration
inspiration: -5 to -7.5 cm H2O expiration: -7.5 to -5 cm H2O
33
define compliance
the extent (volume) to which lungs will expand for each unit increase in the transpulmonary pressure
34
what is normal compliance
200 ml air per cm of water
35
define compliance in terms of the trachea
measure of the expansibility of the lungs and trachea
36
what are the elastic forces of the lungs depicted in the compliance diagram
elastic forces of lung tissue | surface tension within the alveoli
37
what happens when there is an absence of surface tension forces
ease with which lungs can be expanded
38
define elastance
measure of the tendency of a hollow viscus to recoil toward its original dimensions upon removal of a distending or collapsing force
39
what are the most important components of surfactant
dipalmitoylphosphatidylcholine (a phospholipid) surfactant apoproteins calcium ions
40
what produces surfactant
type 2 alveolar cells
41
what happens if air passages leading from the alveoli are blocked, the surface tension in the alveoli collapses the alveoli?
positive pressure is created in the alveoli
42
what happens to the pressure in the alveoli as the radius increases
pressure decreases