lect-22 Pulmonary ventilation Flashcards

1
Q

what is respiratory epithelium

A

pseudo stratified ciliated columnar epithelium with goblet cells

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2
Q

what type of cartilage rings are in the trachea

A

incomplete cartilaginous rings

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3
Q

where are the carina located and what are they sensitive to

A

inside trachea at point of branching of primary bronchi
sensitive to irruption
produces cough reflex

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4
Q

what do the primary bronchi supply to

A

lungs

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5
Q

what do the secondary bronchi supply

A

lobes

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6
Q

what do the tertiary bronchi supply

A

lobules

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7
Q

what type of cartilage is in bronchioles

A

NONE

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8
Q

where is the first place in the respiratory tree that you can get gas exchange

A

respiratory branches of bronchioles

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9
Q

what respiratory muscles are inspiratory

A
respiratory diaphragm
external intercostal muscles (limited)
sternomastoids
serratus anterior muscles
scalene muscles
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10
Q

what muscles are form forceful expiration

A

abdominal muscles

internal intercostals

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11
Q

define total lung capacity

A

maximum volume of gas the lungs can hold

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12
Q

define volumes

A

distinct, non-overlapping sub-compartments referred to as lung volumes

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13
Q

define tidal volume

A

500 ml

volume of air that is inspired or expired with each breath at rest

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14
Q

define inspiratory reserve volume

A

3000 ml

volume of air that can be inspired in addition to tidal volume with forceful inspiration

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15
Q

define expiratory reserve volume

A

1100ml

additional volume of air that can be expired at end of tidal volume by forceful expiration

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16
Q

define residual volume

A

1200 ml

volume of air remaining in lungs after forceful expiration

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17
Q

define vital capacity

A

4600 ml
sum of all the volumes that can be inspired or exhaled
inspiration to the max extent plus expiration to the max extent

18
Q

define total lung capacity

A

5800 ml

the sum of all the volumes= vital capacity plus residual volume

19
Q

define inspiratory capacity

A

3500 ml

the sum of volumes above resting capacity= tidal volume plus inspiratory reserve volume

20
Q

define functional residual capacity

A

2300 ml

the sum of volumes below resting capacity= expiratory reserve volume + residual volume

21
Q

define minute ventilation

A

total volume of gases moved into or out of the lungs per minute

22
Q

define alveolar ventilation

A

total volume of gases that enter spaces participating in gas exchange per minute

23
Q

what is found in the anatomical dead space

A

trachea, bronchi, bronchioles

24
Q

what is found in the physiological dead space

A

anatomical dead space + ventilated alveoli with poor or absent perfusion

25
Q

what is the total dead space in a normal person

A

0.15 liters

26
Q

what is the normal tidal volume

A

0.35 liters

27
Q

what does the amount of CO2 in regions of lungs involved in gas exchange equal

A

that of arterial blood

28
Q

define pleural pressure

A

pressure of the fluid between parietal pleura and the visceral pleura

29
Q

define alveolar pressure

A

pressure of the air inside of the alveoli

30
Q

define transpulmonary pressure

A

difference between the alveolar pressure and the pleural pressure

31
Q

how is pleural pressure measured

A

measured in centimeters of water

32
Q

what is pleural pressure during inspiration and expiration

A

inspiration: -5 to -7.5 cm H2O
expiration: -7.5 to -5 cm H2O

33
Q

define compliance

A

the extent (volume) to which lungs will expand for each unit increase in the transpulmonary pressure

34
Q

what is normal compliance

A

200 ml air per cm of water

35
Q

define compliance in terms of the trachea

A

measure of the expansibility of the lungs and trachea

36
Q

what are the elastic forces of the lungs depicted in the compliance diagram

A

elastic forces of lung tissue

surface tension within the alveoli

37
Q

what happens when there is an absence of surface tension forces

A

ease with which lungs can be expanded

38
Q

define elastance

A

measure of the tendency of a hollow viscus to recoil toward its original dimensions upon removal of a distending or collapsing force

39
Q

what are the most important components of surfactant

A

dipalmitoylphosphatidylcholine (a phospholipid)
surfactant apoproteins
calcium ions

40
Q

what produces surfactant

A

type 2 alveolar cells

41
Q

what happens if air passages leading from the alveoli are blocked, the surface tension in the alveoli collapses the alveoli?

A

positive pressure is created in the alveoli

42
Q

what happens to the pressure in the alveoli as the radius increases

A

pressure decreases