Lect 27 Stem Cells

Question 1

Founder cells are ______ and restore ____ organ cells. They give rise to ____ ____ ____, which are committed to dividing into a certain cell/tissue for a specific, limited number of times

Answer 1

Founder cells are multipotent and restore adult organ cells.

Give rise to Transit Amplifying Cells

Question 2

Embryonic stem cells (ES) can be matured into different types of organ cell systems with treatment of _____ ____.

Answer 2

Retinoic acid

Question 3

_____, ____, ____, and ____ can retroactively turn fibroblasts and somatic cells into ___ cells

Answer 3

Oct3/4, Sox2, Myc, and KIF4

turn adult cells into iPS cells (induced pluripotent stem cells)

Question 4

Adult stem cells from bone marrow (BMSC) and adipose (AMSC) tissues can be used to create ______, ____, and _____ cells for treatment

Answer 4

pancreatic B-cells, osteoblasts, and neuronal-like cells

Question 5

If you can’t use in-vitro fertilization to procure ES due to ethical issues, what would be the best alternative?

Answer 5

Somatic cell nuclear transfer