[LEC] Unit 9: RNA Viruses (Part 1)

Question 1

Icosahedral RNA Naked Viruses

Answer 1

PSCH

Picornaviridae
Sedoreoviridae
Caliciviridae
Hepeviridae

Question 2

Icosahedral RNA Enveloped Viruses

Answer 2

FaTiMa Raine

Flaviviridae
Togaviridae
Matonaviridae
Retroviridae

Question 3

Helical RNA Enveloped Viruses

Answer 3

POP RFC

Paramyxoviridae
Orthomyxoviridae
Pneumoviridae
Rhabdoviridae
Filoviridae
Coronaviridae

Question 4

T or F: Picornaviridae is a Positive sense Single stranded RNA virus

Answer 4

T

Question 5

Genus and Infections under Picornaviridae

Answer 5

EH PuK

Enterovirus - enteric tract
Hepatovirus - liver
Parechovirus
Kobuvirus

Question 6

Genus of Poliovirus

Answer 6

Enterovirus

Question 7

MOT of Poliovirus

Answer 7

Oral-fecal

Question 8

Sie of replication of Poliovirus

Answer 8

Oropharynx and Intestinal tract

Question 9

Smallest virus among Picornaviruses

Answer 9

Poliovirus

Question 10

Agent of atrophy

Answer 10

Poliovirus

Question 11

2 vaccines against Polio

Answer 11

Sabin - oral
Salk - IM

Question 12

Disease caused by Poliovirus

Answer 12

Poliomyelitis (Polio)

Question 13

Known politicians associated with polio

Answer 13

Franklin D. Roosevelt (FDR)
Apolinario Mabini

Question 14

Genus of Coxsackie virus

Answer 14

Enterovirus

Question 15

Second most common virus

Answer 15

Coxsackie virus

Question 16

MOT of Coxsackie virus

Answer 16

Inamoy at kinain yung socks

Oral-fecal
Respiratory aerosols

Question 17

Coxsackie virus: Group A specific disease

Answer 17

HaHe

Herpangina
Hand, foot, and mouth disease or A16 disease

Question 18

Coxsackie virus: Group B specific disease

Answer 18

My PP

Pleurodynia or Bornholm disease
Myocarditis
Pericarditis

Question 19

Genus of Echovirus

Answer 19

Enterovirus

Question 20

Meaning of ECHO in Echovirus

Answer 20

Enteric Cytopathogenic Human Orphan

Question 21

Leading cause of aseptic meningitis

Answer 21

Echovirus

Question 22

Lab dx of Echovirus

Answer 22

Cell culture

Question 23

T or F: Serological test can be used to diagnose echovirus infection

Answer 23

F

It indicates past infection

Question 24

Formerly a Genus

Answer 24

Human Rhinovirus A, B, C

Question 25

T or F: Rhinovirus infects nose and throat

Answer 25

T

Question 26

Agent of common colds

Answer 26

Human Rhinovirus A, B, C

Question 27

Acid labile

Answer 27

Human Rhinovirus A, B, C

Question 28

MOT of Human Rhinovirus A, B, C

Answer 28

Contact with contaminated hands

Question 29

Human Rhinovirus A, B, C grow better at what temperature

Answer 29

33°C

Question 30

Genus of Hepatovirus A

Answer 30

Hepatovirus

Question 31

Hepatovirus A is formerly

Answer 31

Hepatitis A Virus

Question 32

Who discovered HBV? When?

Answer 32

Dr. Baruch Blumburg; 1963

Question 33

When was hepatitis A discovered?

Answer 33

1673

Question 34

MOT of Hepatovirus A

Answer 34

Oral-fecal route

Question 35

Acid stable

Answer 35

Hepatovirus A

Question 36

Hepatovirus A can withstand _____ for ___ hour

Answer 36

56-60°C ; 1

Question 37

T or F: Hepatovirus A is acid stable but can be destroyed by autoclaving and boiling

Answer 37

T

Question 38

Prevention of Hepatovirus A

Answer 38

Vaccination

Question 39

Aka Short Incubation Hepatitis

Answer 39

Hepatovirus A

Question 40

T or F: HAV and HBV are associated with chronic infections

Answer 40

F HBV only

Question 41

3 Hepatitis A Serological Markers

Answer 41

Anti-HAV - detects total antibody Anti-HAV IgM - recent infection (<6 mos) HAV RNA - viral replication marker

Question 42

T or F: HAV Ag is not used to diagnose Hepa A

Answer 42

T It can no longer be detected in stool once S/S are present

Question 43

Genus of Human Parechovirus A (HPeV1) and Ljungan virus

Answer 43

Parechovirus

Question 44

Human Parechovirus A (HPeV1) was formerly

Answer 44

Enterovirus 22

Question 45

Ljungan virus or Parechovirus B

Answer 45

Enterovirus 23

Question 46

Causes zoonotic infection among bank, vole, and wild rodents

Answer 46

Ljungan virus / Parechovirus B

Question 47

Associated with malformations, diabetes, intrauterine deaths and sudden infant deaths in human

Answer 47

Ljungan virus / Parechovirus B

Question 48

Genus of Aichivirus A

Answer 48

Kobuvirus

Question 49

Aichivirus A was formerly

Answer 49

Aichi virus

Question 50

Aichivirus A was identified in

Answer 50

1989 outbreak of AGE in Aichi Prefecture

Question 51

Meaning of AGE

Answer 51

Acute Gastroenteritis

Question 52

T or F: Not much is known about the epidemiology of Aichivirus A

Answer 52

T

Question 53

Oyster-related

Answer 53

Aichivirus A

Question 54

Sedoreoviridae was formerly

Answer 54

Reoveridae

Question 55

Meaning of REO

Answer 55

Respiratory Enteric Orphan

Question 56

Sedoreoviridae is a ______ stranded RNA virus

Answer 56

single

Question 57

Sedoreoviridae was first isolated in

Answer 57

respiratory tract and enteric tract

Question 58

Genus of Rotavirus (ABCDEFGHIJ)

Answer 58

Rotavirus

Question 59

Rotavirus was formerly

Answer 59

Aichi virus

Question 60

Distinct wheel-shaped appearance

Answer 60

Rotavirus (ABCDEFGHIJ)

Question 61

Rotavirus causes

Answer 61

upper and lower respiratory tract disease gastroenteritis diarrhea

Question 62

MOT of Rotavirus (ABCDEFGHIJ)

Answer 62

Oral-fecal route

Question 63

Lab dx of Rotavirus (ABCDEFGHIJ)

Answer 63

Stool (RNA) Elisa

Question 64

Rotavirus A

Answer 64

*A human* disease in humans

Question 65

Rotavirus A-I

Answer 65

*A-nImal* diseases in other animals

Question 66

Rotavirus H

Answer 66

pigs

Question 67

Rotavirus DFG

Answer 67

*in Da FoG* birds

Question 68

Rotavirus I

Answer 68

cats

Question 69

Rotavirus J

Answer 69

bats

Question 70

T or F: Caliciviridae is a Single stranded RNA virus positive sense

Answer 70

T

Question 71

T or F: Calyx = Goblet

Answer 71

T

Question 72

Genus of Norwalk virus

Answer 72

Norovirus

Question 73

Cause outbreaks of AGE in schools and camps

Answer 73

Norwalk virus

Question 74

Norwalk virus is also called

Answer 74

Winter vomiting virus

Question 75

MOT of Norwalk virus

Answer 75

Oral-fecal route Airborne

Question 76

Genus of Sapporo virus

Answer 76

Sapovirus

Question 77

Common cause of AGE

Answer 77

Sapporo virus

Question 78

MOT of Sapporo virus

Answer 78

Oral-fecal route

Question 79

T or F: Hepeviridae is a Single stranded RNA virus positive sense

Answer 79

T

Question 80

Hepatitis E virus was once part of

Answer 80

Caliciviridae

Question 81

Genus of Orthohepevirus A or Hepatitis E Virus

Answer 81

Orthohepevirus

Question 82

Causes Hepa E

Answer 82

Orthohepevirus A

Question 83

Orthohepevirus A was first isolated in year

Answer 83

1990

Question 84

T or F: Hepa E is foodborne

Answer 84

F waterborne

Question 85

MOT of Orthohepevirus A or Hepatitis E Virus

Answer 85

Oral-fecal route

Question 86

Lab dx of Orthohepevirus A

Answer 86

Western blot EM PCR

Question 87

T or F: In a quasi-enveloped particle, the RNA and protein shell are completely enclosed within a membrane that is released from the host cell.

Answer 87

T

Question 88

In a quasi-enveloped particle, the membrane protects the protein shell from

Answer 88

human immune response

Question 89

Stealthy fashion means

Answer 89

The virus will not be recognized by the immune system

Question 90

The term quasi-enveloped virus was introduced in _____ to describe an unusual virion type of Hepatitis A virus (HAV) and Hepatitis E virus (HEV)

Answer 90

2014

Question 91

Both _____ and _____ are enterically transmitted RNA viruses historically considered to be nonenveloped However, recent studies have found that these viruses circulate in the blood stream of infected persons or non- human primates in membrane-wrapped forms that coexist with neutralizing antibodies

Answer 91

HAV; HEV