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MT6322 > [LEC] Unit 9: RNA Viruses (Part 1) > Flashcards

[LEC] Unit 9: RNA Viruses (Part 1) Flashcards

1
Q

Icosahedral RNA Naked Viruses

A

PSCH

Picornaviridae
Sedoreoviridae
Caliciviridae
Hepeviridae

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2
Q

Icosahedral RNA Enveloped Viruses

A

FaTiMa Raine

Flaviviridae
Togaviridae
Matonaviridae
Retroviridae

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3
Q

Helical RNA Enveloped Viruses

A

POP RFC

Paramyxoviridae
Orthomyxoviridae
Pneumoviridae
Rhabdoviridae
Filoviridae
Coronaviridae

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4
Q

T or F: Picornaviridae is a Positive sense Single stranded RNA virus

A

T

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5
Q

Genus and Infections under Picornaviridae

A

EH PuK

Enterovirus - enteric tract
Hepatovirus - liver
Parechovirus
Kobuvirus

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6
Q

Genus of Poliovirus

A

Enterovirus

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7
Q

MOT of Poliovirus

A

Oral-fecal

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8
Q

Sie of replication of Poliovirus

A

Oropharynx and Intestinal tract

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9
Q

Smallest virus among Picornaviruses

A

Poliovirus

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10
Q

Agent of atrophy

A

Poliovirus

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11
Q

2 vaccines against Polio

A

Sabin - oral
Salk - IM

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12
Q

Disease caused by Poliovirus

A

Poliomyelitis (Polio)

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13
Q

Known politicians associated with polio

A

Franklin D. Roosevelt (FDR)
Apolinario Mabini

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14
Q

Genus of Coxsackie virus

A

Enterovirus

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15
Q

Second most common virus

A

Coxsackie virus

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16
Q

MOT of Coxsackie virus

A

Inamoy at kinain yung socks

Oral-fecal
Respiratory aerosols

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17
Q

Coxsackie virus: Group A specific disease

A

HaHe

Herpangina
Hand, foot, and mouth disease or A16 disease

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18
Q

Coxsackie virus: Group B specific disease

A

My PP

Pleurodynia or Bornholm disease
Myocarditis
Pericarditis

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19
Q

Genus of Echovirus

A

Enterovirus

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20
Q

Meaning of ECHO in Echovirus

A

Enteric Cytopathogenic Human Orphan

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21
Q

Leading cause of aseptic meningitis

A

Echovirus

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22
Q

Lab dx of Echovirus

A

Cell culture

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23
Q

T or F: Serological test can be used to diagnose echovirus infection

A

F

It indicates past infection

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24
Q

Formerly a Genus

A

Human Rhinovirus A, B, C

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25
Q

T or F: Rhinovirus infects nose and throat

A

T

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26
Q

Agent of common colds

A

Human Rhinovirus A, B, C

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27
Q

Acid labile

A

Human Rhinovirus A, B, C

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28
Q

MOT of Human Rhinovirus A, B, C

A

Contact with contaminated hands

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29
Q

Human Rhinovirus A, B, C grow better at what temperature

A

33°C

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30
Q

Genus of Hepatovirus A

A

Hepatovirus

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31
Q

Hepatovirus A is formerly

A

Hepatitis A Virus

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32
Q

Who discovered HBV? When?

A

Dr. Baruch Blumburg; 1963

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33
Q

When was hepatitis A discovered?

A

1673

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34
Q

MOT of Hepatovirus A

A

Oral-fecal route

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35
Q

Acid stable

A

Hepatovirus A

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36
Q

Hepatovirus A can withstand _____ for ___ hour

A

56-60°C ; 1

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37
Q

T or F: Hepatovirus A is acid stable but can be destroyed by autoclaving and boiling

A

T

38
Q

Prevention of Hepatovirus A

A

Vaccination

39
Q

Aka Short Incubation Hepatitis

A

Hepatovirus A

40
Q

T or F: HAV and HBV are associated with chronic infections

A

F

HBV only

41
Q

3 Hepatitis A Serological Markers

A

Anti-HAV
- detects total antibody

Anti-HAV IgM
- recent infection (<6 mos)

HAV RNA
- viral replication marker

42
Q

T or F: HAV Ag is not used to diagnose Hepa A

A

T

It can no longer be detected in stool once S/S are present

43
Q

Genus of Human Parechovirus A (HPeV1) and Ljungan virus

A

Parechovirus

44
Q

Human Parechovirus A (HPeV1) was formerly

A

Enterovirus 22

45
Q

Ljungan virus or Parechovirus B

A

Enterovirus 23

46
Q

Causes zoonotic infection among bank, vole, and wild rodents

A

Ljungan virus / Parechovirus B

47
Q

Associated with malformations, diabetes, intrauterine deaths and sudden infant deaths in human

A

Ljungan virus / Parechovirus B

48
Q

Genus of Aichivirus A

A

Kobuvirus

49
Q

Aichivirus A was formerly

A

Aichi virus

50
Q

Aichivirus A was identified in

A

1989 outbreak of AGE in Aichi Prefecture

51
Q

Meaning of AGE

A

Acute Gastroenteritis

52
Q

T or F: Not much is known about the epidemiology of Aichivirus A

A

T

53
Q

Oyster-related

A

Aichivirus A

54
Q

Sedoreoviridae was formerly

A

Reoveridae

55
Q

Meaning of REO

A

Respiratory Enteric Orphan

56
Q

Sedoreoviridae is a ______ stranded RNA virus

A

single

57
Q

Sedoreoviridae was first isolated in

A

respiratory tract and enteric tract

58
Q

Genus of Rotavirus (ABCDEFGHIJ)

A

Rotavirus

59
Q

Rotavirus was formerly

A

Aichi virus

60
Q

Distinct wheel-shaped appearance

A

Rotavirus (ABCDEFGHIJ)

61
Q

Rotavirus causes

A

upper and lower respiratory tract disease
gastroenteritis
diarrhea

62
Q

MOT of Rotavirus (ABCDEFGHIJ)

A

Oral-fecal route

63
Q

Lab dx of Rotavirus (ABCDEFGHIJ)

A

Stool (RNA)
Elisa

64
Q

Rotavirus A

A

A human

disease in humans

65
Q

Rotavirus A-I

A

A-nImal

diseases in other animals

66
Q

Rotavirus H

A

pigs

67
Q

Rotavirus DFG

A

in Da FoG

birds

68
Q

Rotavirus I

A

cats

69
Q

Rotavirus J

A

bats

70
Q

T or F: Caliciviridae is a Single stranded RNA virus positive sense

A

T

71
Q

T or F: Calyx = Goblet

A

T

72
Q

Genus of Norwalk virus

A

Norovirus

73
Q

Cause outbreaks of AGE in schools and camps

A

Norwalk virus

74
Q

Norwalk virus is also called

A

Winter vomiting virus

75
Q

MOT of Norwalk virus

A

Oral-fecal route
Airborne

76
Q

Genus of Sapporo virus

A

Sapovirus

77
Q

Common cause of AGE

A

Sapporo virus

78
Q

MOT of Sapporo virus

A

Oral-fecal route

79
Q

T or F: Hepeviridae is a Single stranded RNA virus positive sense

A

T

80
Q

Hepatitis E virus was once part of

A

Caliciviridae

81
Q

Genus of Orthohepevirus A or Hepatitis E Virus

A

Orthohepevirus

82
Q

Causes Hepa E

A

Orthohepevirus A

83
Q

Orthohepevirus A was first isolated in year

A

1990

84
Q

T or F: Hepa E is foodborne

A

F

waterborne

85
Q

MOT of Orthohepevirus A or Hepatitis E Virus

A

Oral-fecal route

86
Q

Lab dx of Orthohepevirus A

A

Western blot
EM
PCR

87
Q

T or F: In a quasi-enveloped particle, the RNA and protein shell are completely enclosed within a membrane that is released from the host cell.

A

T

88
Q

In a quasi-enveloped particle, the membrane protects the protein shell from

A

human immune response

89
Q

Stealthy fashion means

A

The virus will not be recognized by the immune system

90
Q

The term quasi-enveloped virus was introduced in _____ to describe an unusual virion type of Hepatitis A virus (HAV) and Hepatitis E virus (HEV)

A

2014

91
Q

Both _____ and _____ are enterically transmitted RNA viruses historically considered to be nonenveloped
However, recent studies have found that these viruses circulate in the blood stream of infected persons or non- human primates in membrane-wrapped forms that coexist with neutralizing antibodies

A

HAV; HEV

MT6322 (4 decks)

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