[LEC] LESSON 1: INTRODUCTION TO URINALYSIS Flashcards
- 5th century BC wrote a book on “uroscopy”
Hippocrates
- uroscopy has been a part of the physician’s training
Middle ages
- color charts had been developed that described the significance of 20 different colors.
1140 AD
- discovery of albuminuria by boiling urine
Fredrik Dekkers (1694)
- published a book about the credibility of urinalysis that inspired the passing of the first medical licensure laws in England.
Thomas Bryant (1627)
- Addis count was developed
- quantitation of microscopic sediments
Thomas Addis (17th Century)
Richard Bright (1827)
introduced the concept of urinalysis as a part of routine patient examination.
Aqueous solution of various organic and inorganic substances
Urine
Substance may be either waste products resulting from body metabolism or products derived directly from the food eaten resulting from metabolism.
Urine
(?) water and (?) solids
95%
5%
- It is readily available and (?).
easily collected
- Contains information about the body’s major (?) functions
metabolic
- (?) laboratory testing can be performed.
Inexpensive
- It is most useful in ascertaining (?) of disease or disturbing function of the kidneys
evidence
- Pathological lesion of the (?)
ureters, bladder or urethra
- In male, lesion of the (?).
prostate and seminal vesicles
60 to 90% of nitrogenous material derived from metabolism of amino acids into ammonia
Urea
Derived from creatine, nitrogenous substance in muscle tissue
Creatinine
Common component of kidney stones, derived from catabolism of nucleic acid in food and cell destruction
Uric acid
Elimination form of a benzoic acid furic acid
Hippuric acid
Increases with high vegetable diets
Hippuric acid
Carbohydrates, pigments, fatty acids, mucin, enzymes, hormones (depends on diet and health)
Other substances
Urea in g
25 to 35
Creatinine in g
1.5