(LEC) Last Prelims Quiz Flashcards
Antibiotic produced by Bacillus subtilis
Bacitracin
Antibiotic produced by Bacillus polymyxa
Polymyxin
Antibiotic produced by Cephalosporium
Cephalosporins
Antibiotic produced by Micromonospora purpurea
Gentamicin
Antibiotic produced by Penicillium notatum
Penicillin
Antibiotic produced by Streptomyces erythraeus
Erythromycin
Antibiotic produced by Streptomyces fradiae
Neomycin
Streptomyces nodusus
Amphotericin B
Antibiotic produced by Streptomycin noursei
Nystatin
Antibiotic produced by Streptomyces venezuelae
Chloramphenicol
Drugs that are produced by bacteria or fungi
Natural Drugs
Modified natural drugs with added chemical groups
Semi-Synthetic Drugs
Chemically produced drugs
Synthetic Drugs
Natural Drugs
Amphotericin B
Erythromycin
Kanamycin
Penicillin
Semi-synthetic drugs
Ampicillin
Carbapenicillin
Methicillin
Synthetic Drugs
Sulfinamides
Trimethoprim
Ciproflixacin
Isoniazid
These are antimicrobial agents that inhibit bacterial growth
Bacteriostatic Agents
These are antiomicrobial agents that usually kill or destroy organisms
Bactericidal Agents
Lowest Concentration of drug that inhibits bacterial growth
Minimal Inhibitory Concentration
Ratio if the toxic dose to the therapeutic dose
Minimum Therapeutic Index
Most selective antibiotics with a higher therapeutic index
Cell Wall Inhibitors
Cell Wall Inhibitors inhibit the activity of what enzyme
Transpeptidase Enzymes
Cell wall inhibitor that inhibits synthesis if peptidoglycan precursors
Bacitracin
Cell wall inhibitor that inhibits transpeptidation
B-lactams
Cell wall inhibitor that inhibits translocation and elongation of peptidoglycan
Vancomycin
Protein Synthesis Inhibitors bind to to what subunit
30S
Targets of Protein Synthesis Inhibitors
Aerobic and Anaerobic Gram(+) and Gram(-) bacteria
Inhibits RNA polymerase and synthesis
Rifampicin
Effective Nucleic Acid Synthesis Inhibitor for Enteric Bacteria
Quinolones
Disrupts DNA and effective against anaerobic bscteria
Metronidazole
Cell membrane inhibitors effective against gram(-) bacteria
Polymyxin B
Polymyxin E
Folic Acid Inhibitor
Sulfamethoxazole
Cord Factor Inhibitors
Isoniazid
Measures the antibiotic or other microbial agent to inhibit bacterial growth
Antimicrobial Susceptibility Testing
Disk Diffusion Method is aka
Kirby-Bauer Test
Culture Method sued for Disk Diffusion Method
Mueller-Hinton Method
pH for Disk Diffusion Method
pH 7.2 - 7.4
The standard susceptibility medium for non-fastidious bacteria
Mueller-Hinton Agar
Added to MH Broth to be used to improve the detection of oxacillin-resistant staphylococci
2% NaCl
Added to MH Broth to be utilized for testing susceptibility for streptococci, N. meningitis, and other fastidious organisms
5% Lysed Horse Blood
Disk Diffusion Method is Aerobic except when testing with
Capnophiles
Decrease in pH during Kirby Bauer Method affects what
Microbes
Increase in pH during Kirby Bauer Method affects what
Antibiotics
100mm diameter can have how many disks
6 disks
A 150mm plate can have a maximum of how many disks
12 disks
Kirby-Bauer Test Result of a 15min delay in application
False Resistant
Kirby-Bauer Test Result of a 15min delay in incubation
False Sensitive
Diameter of each zone in Disk Diffusion Method is measured using what
Caliper
Disk Diffusion Result if the microorganism responds to the therapy with that antimicrobial agent
Susceptible