lec 8: nucleotides Flashcards
DNA from DNA
replication
RNA from DNA
transcription
protein from RNA
translation
arrangement of genes
chromosomes
total genetic information
genome
purine bases
adenine & guanine
pyrimidine bases
thymine, uracil, cytosine
importance of free nucleotides
- energy sources (AMP,ADP,ATP)
- sulphate donor (PAP)
- coenzymes: hydrogen carriers (NAD, NADP, FAD)
- secondary messengers (cyclic AMP, cyclic GMP)
- methyl donor: SAM (adenine nucleoside)
methyl donor
SAM
sulphate donor
PAP
hydrogen donors
NADP, NAD, FAD
carrier of amino acid from cytosol to ribosome in process of protein synthesis
tRNA
synthesized in nucleus then passed to ribosomes
mRNA
80% of total RNA
ribosomal RNA
site for protein synthesis
ribosomal RNA
purines of DNA and RNA
adenine and guanine
pyrimidines of DNA
cytosine, thymine
pyrimidines of RNA
cytosine, uracil
sugar of DNA
2 de-oxyribose
sugar of RNA
ribose
site of DNA
nucleus and mitochondria
site of RNA
mainly in cytosol, less commonly in nucleus and mitochondria
functions of DNA
genetic information and RNA synthesis
function of RNA
protein synthesis