Lec 5-Respiration Regulation

Question 1

Is primary stimulus for neurons at the respiratory centre in the brain stem so as to increase respiratory rate

Answer 1

hydrogen ions

Question 2

Name the 3 groups of neurons at the respiratory centre, and their roles

Answer 2

1. Dorsal respiratory group
   * Processes imputs from lungs and chemoreceptors
   * Provides excitatory inspiratory stimuli to phrenic motor neurons
   * Play the main role in the control of respiration
2. Ventral respiratory group
   * Inactive during normal breathing
   * function during increased pulmonary ventilation
   * neurons contribute to both inspiration and expiration
3. Pneumotaxic centre
   * Primary function is to limit inspiration
   * Increases rate of respiration

Question 3

Natural acclamitization of people living in high altitude

Answer 3

• Acclimatization begins in infancy
• Increase chest size
• Reduced body size
• Increased pulmonary vasculature- abnormal enlargement of pulmonary vessels
• Increased right heart size
• Increased Hb affinity for oxygen

Question 4

What are the 5 means of acclimitization? Likewhat happens during acclamitization

Answer 4

Increased:
1. Pulmonary ventilation
2. Red blood cells
3. Diffusing capacity
4. Vascularity of tissues
5. Ability of cells to use oxygen

Question 5

Two types of mountain sickness

Answer 5

• acute
• chronic

Question 6

Seen with chronic mountain sickness

Answer 6

• Increased RBCs and hematocrit
• Increased arterial pulmonary pressure
• Right heart failure