Lec 1 Flashcards
What is the objective of the Radiopharmacy course?
To provide students with the knowledge and skills regarding producing, designing, quality control, application, and regulation of radiopharmaceuticals in pharmacy and medicine.
List the main topics covered in the Radiopharmacy course.
- Introduction to the course
- Basic physics of Radiation
- Production of Radionuclides
- Production of Radiochemicals, Technetium (Tc-99m)
- Production of Radiopharmaceuticals
- Routine work in the Radiopharmacy (Hot lab)
- QC of Radiopharmaceuticals
- Examples of Organ Imaging (SPECT technology)
- Radiation Protection
- Advances in Radiopharmacy
What are the key components of the scope of Radiopharmacy?
- The Atom (Electronic Structure, different chemical bonds)
- Radioactive Decay (Decay of Radionuclides, Units of Radioactivity)
- Instruments for Radiation Detection and Measurement
- Production of Radionuclides (reactors, accelerators, Generators)
- Radionuclide Generators (Principles, Important Generators)
- Radiopharmaceuticals and Methods of Radiolabeling
- Characteristics of Specific Radiopharmaceuticals
- Quality Control of Radiopharmaceuticals
- Nuclear Pharmacy concept
- Therapeutics of Radiopharmaceuticals
- Radioactive waste management
- Radiation protection
- Radiopharmacy layout
What was a significant development in Radiopharmacy during 1960?
Development of Tc-99m Generator, which revolutionized Radiopharmacy.
Define Radiopharmacy.
Radiopharmacy is a specialty area of pharmacy practice dedicated to the compounding and dispensing of radioactive materials for use in nuclear medicine procedures.
What is a Radiopharmaceutical?
A pharmaceutical substance containing radioactive atoms (radionuclide) within its structure, used for diagnostic and therapeutic treatment.
True or False: Radiopharmaceuticals are only used in diagnostic applications.
False
What are the primary uses of Radiopharmaceuticals?
- Diagnostic medical imaging
- Therapeutic applications (e.g., treatment of hyperthyroidism, thyroid cancer, polycythemia vera, alleviation of bone pain)
Fill in the blank: A _______ is a professional with a state license as a pharmacist or nuclear pharmacist who meets local/international training requirements.
Radiopharmacist
What governs the distribution of radionuclides in the body?
- Their physicochemical properties
- Pharmacokinetic properties
What methodologies are included in diagnostic Nuclear Medicine?
- Study of perfusion
- Regional blood flow
- Metabolic pathways
- Biodistribution
- Kinetics
What is the role of radiopharmaceuticals in imaging?
They allow for imaging of organ morphology, function, and disease states.
What type of radiation do most radiopharmaceuticals used in diagnostic Nuclear Medicine procedures emit?
Gamma radiation.
Define radionuclides.
Radionuclides are disintegrated with the emission of nuclear particles or photons.
What is a cold kit in Radiopharmacy?
Non-radioactive compounds that are easy to store and used for the preparation of radiopharmaceuticals.
What is the significance of quality control (QC) in Radiopharmaceuticals?
Ensures the safety, efficacy, and proper dosage of radiopharmaceuticals for patient use.
What is the main imaging device used in Radiopharmacy?
Gamma camera.
