Leaves: Glycyrrhiza Glabra (Licorice) Leaf Extract Flashcards
1
Q
What are the important bioactives extracted from the root?
A
- glycyrrhizin acid
50 times sweeter than sugar
gives licorice its notable flavor - glabridin
- flavonoid content i.e. liquiritin and isoliquiritin
yellow color
antioxidant-rich
decrease reactive oxygen species
anti-inflammatory properties
2
Q
What are the mechanisms of glycyrrhizin?
A
- does not scavenge free radicals
- reduces inflammation by inhibiting free radical generation
- prevents swelling and redness
3
Q
What are the benefits of Liquiritin?
A
UV Protection
* suppresses UVB-induced cell damage
* prevents inflammation and oxidative stress
* inhibits proteins that cause inflammation
* downregulates release of oxidants that cause oxidative stress
4
Q
What are the benefits of Glabridin?
A
Prevents and treats dark spots
* natural lightening alternative to hydroquinone
* treat and prevent pigmentation
5
Q
How does licorice root work for hyperpigmentation?
A
Glabridin in licorice inhibits the production of tyrosinase, the key enzyme involved in melanin production.
6
Q
Why use licorice for dark spots?
A
No photosensitivity or toxicity risks vs hydroquinone.
