Lead Poisoning Flashcards
1
Q
What does lead poisoning cause?
A
Anemia (disrupts hemoglobin synthesis)
Neurotoxicity
2
Q
How do pediatrics patients get lead poisoning?
A
Lead based paint (toys, old house, remodeling)
3
Q
How do adult patients get lead poisoning?
A
Battery manufacturing, lead/zinc mining
4
Q
Pathophysiology
A
Inhibits delta-aminolevulinic acid dehydratase and ferrochelatase
5
Q
Basophilic stippling
A
lead causes degradation of rRNA in RBCs
6
Q
Treatment
A
Remove lead source
Dimercaptosuccinic acid (DMSA)
Dimercaprol
CaEDTA