Bullous Pemphigoid vs. Pemphigus Vulgaris Flashcards by Kaoru Song | Brainscape

Q

Antibodies against desmosomes

A

Pemphigus vulgaris

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Q

Antibodies against hemidesmosomes

A

Bullous pemphigoid

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Q

Microscopically see acantholysis

A

Pemphigus vulgaris

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Q

Painful, flaccid blisters

A

Pemphigus vulgaris

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Q

Tense bullae are difficult to rupture

A

Bullous pemphigoid

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Q

Nikolsky sign positive

A

Pemphigus vulgaris

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Q

Nikolsky sign negative

A

Bullous pemphigoid

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Q

Rare oral lesions

A

Bullous pemphigoid

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Q

Oral lesions present

A

Pemphigus vulgaris

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Q

Treatment: 1st line: high dose system steroids

A

Pemphigus vulgaris

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Q

Treatment: 1st line: topical steroids like clobetasol

A

Bullous pemphigoid

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Q

Poor prognosis / 5% mortality

A

Pemphigus vulgaris

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Q

Good prognosis

A

Bullous pemphigoid

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