LE6 Flashcards
- A diagnostic tool with a high sensitivity and a low specificity is best used as:
A. Screening tool for the presence/absence of disease
B. Confirmatory tool for the presence/absence of disease
C. . Both for screening and confirmation of disease
D. A test to rule in a negative test result
A. Screening tool for the presence/absence of disease
- A NEW diagnostic tool for COVID-19 is discovered. Called the COVID breath test, it claims to have a sensitivity of 90% and a specificity of 95% when compared to the GOLD STANDARD of RT-PCR testing. In a population of 2750 and an COVID-19 prevalance of 3%, answer the following:
How many patients are expected to test positive for the breath test?
A. 82
B. 208
C. 5
D. 2506
A. 82
- A NEW diagnostic tool for COVID-19 is discovered. Called the COVID breath test, it claims to have a sensitivity of 90% and a specificity of 95% when compared to the GOLD STANDARD of RT-PCR testing. In a population of 2750 and an COVID-19 prevalance of 3%, answer the following:
How many patients are expected to test negative for RT-PCR?
A. 76
B. 141
C. 1845
D. 2667
D. 2667
- A NEW diagnostic tool for COVID-19 is discovered. Called the COVID breath test, it claims to have a sensitivity of 90% and a specificity of 95% when compared to the GOLD STANDARD of RT-PCR testing. In a population of 2750 and an COVID-19 prevalance of 3%, answer the following:
How many true positive test results are expected?
A. 75
B. 120
C. 226
D. 1534
A. 75
- A NEW diagnostic tool for COVID-19 is discovered. Called the COVID breath test, it claims to have a sensitivity of 90% and a specificity of 95% when compared to the GOLD STANDARD of RT-PCR testing. In a population of 2750 and an COVID-19 prevalance of 3%, answer the following:
How many true negative test results are expected?
A. 99
B. 145
C. 983
D. 2534
D. 2534
- A NEW diagnostic tool for COVID-19 is discovered. Called the COVID breath test, it claims to have a sensitivity of 90% and a specificity of 95% when compared to the GOLD STANDARD of RT-PCR testing. In a population of 2750 and an COVID-19 prevalance of 3%, answer the following:
How many false negative test results are expected?
A. 10
B. 133
C. 202
D. 1333
B. 133
- A NEW diagnostic tool for COVID-19 is discovered. Called the COVID breath test, it claims to have a sensitivity of 90% and a specificity of 95% when compared to the GOLD STANDARD of RT-PCR testing. In a population of 2750 and an COVID-19 prevalance of 3%, answer the following:
How many false positive test results are expected?
A. 8
B. 78
C. 1255
D. 2602
A. 8
- A NEW diagnostic tool for COVID-19 is discovered. Called the COVID breath test, it claims to have a sensitivity of 90% and a specificity of 95% when compared to the GOLD STANDARD of RT-PCR testing. In a population of 2750 and an COVID-19 prevalance of 3%, answer the following:
How many are expected to test negative for the breath test?
A. 68
B. 357
C. 1987
D. 2542
D. 2542
- A NEW diagnostic tool for COVID-19 is discovered. Called the COVID breath test, it claims to have a sensitivity of 90% and a specificity of 95% when compared to the GOLD STANDARD of RT-PCR testing. In a population of 2750 and an COVID-19 prevalance of 3%, answer the following:
How many are expected to test positive for the RT-PCR confirmatory test?
A. 11
B. 83
C. 567
D. 2334
B. 83
- A NEW diagnostic tool for COVID-19 is discovered. Called the COVID breath test, it claims to have a sensitivity of 90% and a specificity of 95% when compared to the GOLD STANDARD of RT-PCR testing. In a population of 2750 and an COVID-19 prevalance of 3%, answer the following:
A patient comes to you with a negative test result. What is the possibility that the test result is wrong?
A. 1%
B. 75%
C. 94%
D. 98%
A. 1%
11.A NEW diagnostic tool for COVID-19 is discovered. Called the COVID breath test, it claims to have a sensitivity of 90% and a specificity of 95% when compared to the GOLD STANDARD of RT-PCR testing. In a population of 2750 and an COVID-19 prevalance of 3%, answer the following:
How many patients are expected to test negative for RT-PCR?
A. the value will increase
B. the value will decrease
A. the value will increase
- A lowering of the cut-off for titers for diagnosis of COVID-19 antibody will sensitivity of the test
A. the value will increase
B. the value will decrease
A. the value will increase
- Type Il or Beta Error that occurs when data lead one to conclude that something is false, when in reality, it is true. The False negative rate suggests that the test is therefore sensitive.
A. Both are True
B. Both are False
C. First is True, Second is False
D. First is False, Second is True
C. First is True, Second is False
- The lower the alpha, the lower the sample size needed.
A. True
B. False
B. False
- Five prospective cohort studies were undertaken to examine the association between bacterial vaginosis and delivery of a premature child. The results of these five hypothetical studies are illustrated in the following figure and are expressed as relative risks with 95% confidence intervals.
Which study has a p-value of >0.5 with data indicating no statistical significance?
A. B
B. A
C. C
D. E
E. D
E. D
- The direction of the relationship is enough to ascertain the strength of the association between variables.
A. True
B. False
B. False
- A new test has been developed to screen for diabetes. The following figure illustrates the distribution of values for this test among two populations. The researcher decides to use values under 20 g/dL as normal limits, and the test becomes commercially available. One of your patients has a test result of 27 ug/dL. You conclude that?
A. The patient has cancer of the diabetes
B. This is a false-negative test
C. This test is not sensitive enough to detect diabetes
D. The patient does not have diabetes
E. A confirmation test will be needed as she may or may not have diabetes
E. A confirmation test will be needed as she may or may not have diabetes
- This illustration shows
A. low precision, low accuracy
B. low precision, high accuracy
C. high precision, low accuracy
D. high precision high accuracy
C. high precision, low accuracy
- Which one is NOT a characteristic of an ideal measure dispersion?
A. it is not affected by extreme values
B. it must be easy to understand
C. it is the most unreliable measure of central tendency
D. it is least affected by sampling fluctuation
C. it is the most unreliable measure of central tendency
- A measure on how close the experimental value is to the true value is
A. accuracy
B. precision
C. both
D. neither
A. accuracy
- Five prospective cohort studies were undertaken to examine the association between bacterial vaginosis and delivery of a premature child. The results of these five hypothetical studies are illustrated in the following figure and are expressed as relative risks with 95% confidence intervals.
Which study appears to be the most precise?
A B
B. D
C. A
D. E
E. C
C. A
- The results of a study of the incidence of pulmonary tuberculosis in a village in Bacoor are given in the following table. All persons in the village are examined during two surveys made two years apart, and the number of new cases was used to determine the incidence rate. If the relative risk of the following data is calculated at 1.6% with a 95% confidence interval of 0.90-2.0. Is this risk statistically significant?
A. Cannot be determined with the data given
B. Yes, because the RR of 1.6% is within the confidence interval.
C. No, because the RR value of no difference is within the confidence interval
C. No, because the RR value of no difference is within the confidence interval
- As test specificity increases, what is the effect on PPV?
A. the value will increase
B. the value will decrease
A. the value will increase
- Statistics enables us to remove the uncertainty of the relationship between variables and approximate a 100% clarity.
A. True
B. False
B. False
26.Which is used to summarize a big data set using less numbers?
A. summarizing
B. cleaning
C. descriptive Statistics
D. analysis
C. descriptive Statistics
- Statistical correlation analysis is possible between qualitative variables
A. True
B. False
B. False
- Categories are used as labels to distinguish one group from another
A. confounders
B. quantitative variables
C. discrete variables
D. qualitative variables
D. qualitative variables
- Multiple variables can be correlated to show regression.
A. True
B. False
A. True
- Precision pertains to all of the following
EXCEPT:
A. reproducibility of measurements
B. agreement among numerical values
C. sameness of measurements
D. loseness of a measurement to an accepted value
D. loseness of a measurement to an accepted value
- The alpha is inversely proportional to the probability of committing a Type Il error
A. True
B. False
A. True
32.A patient resulted negative on a certain cancer screening after biopsy patient tested positive, what can you say about the first result?
A. true positive
B. false positive
C. true negative
D. false negative
D. false negative
- Which deals with an inspection average?
A. mode
B. mean
A. mode
- The value of alpha serves as protection against:
A. false negative results
B. inadequate sample data
C. selection bias
D. type 1 error
E. type I error
D. type 1 error
- If a test of significance gives a value lower than the alpha-level, the null hypothesis is rejected.
A. True
B. False
A. True
- The results of a study of the incidence of pulmonary tuberculosis in a village in Bacoor are given in the following table. All persons in the village are examined during two surveys made two years apart, and the number of new cases was used to determine the incidence rate.Interpret the result ff the calculated relative risk for this survey is at 1.6%.
A. The risk of contracting pulmonary tuberculosis is higher in households with culture positive cases than households without culture positive cases
B. The risk of contracting pulmonary tuberculosis is higher in households without culture positive cases than households with culture positive cases
C. The risk of contracting pulmonary tuberculosis is lower in households with culture positive cases than households without culture positive cases
D. Cannot be determined with the data given
A. The risk of contracting pulmonary tuberculosis is HIGHER in households with culture positive cases than households WITHOUT culture positive cases
- Measurement that is free of random error
A. accuracy
B. precision
C. both
D. neither
D. neither
- Which of the following deals with acute conditions and accidents or newly diagnosed cases of a particular disease?
A. prevalence
B. case fatality rate
C. incidence rate
D. general fertility rate
C. incidence rate
- If the prevalence of a disease has been more or less constant for the past ten years (i.e., new cases have been balanced by cures or deaths of prevalent cases), what would be the effect of a treatment that prolongs the life of people suffering from the disease?
A. increase prevalence
B. decrease prevalence
C. no effect
D. cannot be predicted
A. increase prevalence
- The smaller the probability of being wrong, the more significant is the relationship being statistically significant.
A. True
B. False
A. True
- The number of persons who actually experience the event divided by the total number of persons exposed to the risk of that event is the
A. relative risk
B. absolute risk
C. odds ratio
D. None of the choices is correct
B. absolute risk
- The extent up to which the findings of your investigation can be applied to other settings
A. Internal validity
B. External validity
B. External validity
- The results of a study of the incidence of pulmonary tuberculosis in a village in Bacoor are given in the following table. All persons in the village are examined during two surveys made two years apart, and the number of new cases was used to determine the incidence rate. What is the risk difference between the exposure and non-exposure groups?
A. 6.67%
B. 0.75%
C. 0.77%
D. 3.33%
B. 0.75%
- A new test has been developed to screen for diabetes. The following figure illustrates the distribution of values for this test among two populations.
If the researcher chooses values under 25 ug/dL as normal limits for the test, which of the following statements is true?
A. The test will be 100% sensitive
B. There will be some false-positive tests
C. All persons with cancer will have a positive test
D. Some persons without cancer will test positive
E. The test will be 100% specific
B. There will be some false-positive tests
- Base on the data given: 56, 48, 35, 63, 50, 72, 67, 70, what is the Coefficient of Range?
A. 35
B. 89
С. 107
D. 0.34
D. 0.34
Scenario: Initial results of a nationwide survey on the upcoming elections conducted by Trust Watch show that among 2,400 respondents, Candidate A leads over Candidate B by 23 points. To validate the results, the same study was conducted at the LRT station in Antipolo city among 300 respondents which reveals that Candidate A got 46% while candidate B has 44%, which according to the researchers is NOT statistically significant.
- The second study does not have external validity due to
A. All of the choices are correct
B. The selection of respondents is biased towards those residing in Antipolo
C. The 300 respondents have already been pre-tested
D. the sample size of the nationwide survey is sufficient
B. The selection of respondents is biased towards those residing in Antipolo
- A Type I error occurs when you reject a true hypothesis.
A. True
B. False
B. False
- If rapidly progressive cancers are missed by a screening test, which type of bias will occur?
A. Surveillance bias
B. Information bias
C. Selection bias
D. Length bias
D. Length bias
- The formula for a (+) likelihood ratio is
A. sensitivity/1-specificity
B. specificity/1 - sensitivity
C. 1 - specificity/sensitivity
D. 1- sensitivity.specificity
A. sensitivity/1-specificity
- A research instrument which represents the thing that it aims to indicate is said to have validity.
A. Construct
B. Content
C. Criterion
D. Face
B. Content
- Statistical significance is achieved when:
A. alpha is greatar than or equal to p
B. beta equals alpha
C. p is greater than alpha
D. p is greater than beta
A. alpha is greatar than or equal to p
- The ability of a test to indicate non-disease when no disease is present can be determined with this formula
A. TP / (TP + FN)
B. TN / (TN + FP)
C. TN / (TN + FN)
D. TP / (TP + FP)
B. TN / (TN + FP)
- A null hypothesis states that the proposed relationship is untrue
A. True
B. False
A. True
- Confirmatory Test is used to “rule out” false hypotheses or differential diagnoses.
It must have a high degree of sensitivity and a low FN / type II error rate.
A. both are true
B. Both are False
C. First is True, Second is False
D. First is False, Second is True
C. First is True, Second is False
It must have a high degree of SPECIFICITY and a low FN / type I error rate.
- A data collection method which is able to reflect how close measurements of the same item are to each other has which characteristic?
A. Reliability
B. Persistence
C. Accuracy
D. Validity
A. Reliability
- An investigator is designing a randomized, double-blind,
placebo-controlled clinical trial to see whether vitamin E will prevent lung cancer.
Which is most likely to affect the validity (source of bias) of the study?
A. Loss to follow-up
B. B error
C. Prevalence of smoking in the source population
D. Incidence of lung cancer
E. a error
A. Loss to follow-up
- Get the Range of the given score of students in PMCH 3rd LE: 56, 48, 35, 63,
50, 72, 67, 70
A. 40
B. 52
C. 37
D. 60
C. 37
- Ability of a test to indicate non-disease when no disease is present is
A. sensitivity
B. specificity
C. validity
D. accuracy
B. specificity
- About 1% of boys are born with undescended testes. To determine whether prenatal exposure to tobacco smoke is a cause of undescended testes in newborns, the mothers of 100 newborns with undescended testes and those of 100 newborns whose testes had descended were questioned about smoking habits during pregnancy. The study revealed an odds ratio of 2.6 associated with exposure to smoke, with 95% confidence intervals (CI) from 1.1 to 5.3. Some reviewers are concerned that the study may overestimate the association between maternal smoking and undescended testes in the offspring because of potential
A. Selection bias
B. Confounding
C. Loss to follow-up
D. Recall bias
D. Recall bias
- This is an introduced when a researcher fails to follow the protocol in the conduct of the study
A. Random error
B. Bias
C. Systematic error
D. Confounding
A. Random error
- Barangay X is a community of 100,000 persons in the country. During typhoon Haiyan in 2013, there were 1,000 deaths from all causes. A study of all cases of tuberculosis found the number of deaths at 300 (200 males and 100 females). During
2012, there were only 60 deaths from tuberculosis, 50 of them males. What is the case fatality rate for tuberculosis in 2013?
A. 10/1000
B. 300/100,000
C. cannot be computed from given data
D. 60 per 1000
E. 66
C. cannot be computed from given data
- The accepted value is 29.35. Which correctly describes this student’s experimental data?
A. accurate but not precise
B. precise but not accurate
C. both
D. neither
C. both
- True statement about ratios
A. calculated by multiplying one interval to another
B. represents the relative magnitude of two quantities
C. used to compare a part to the whole
D. The numerator and denominator needs to be related
B. represents the relative magnitude of two quantities
- The mathematical formula for a straight line is y=m+b. The conceptual approach to this formula is not the same in mathematics as in statistics. In statistics:
A. Only m is unknown
B. the equation is irrelevant
C. and y are known, and m and b are to be determined
D. y is known, and x is to be
determined
C. and y are known, and m and b are to be determined
- If a biochemical test gives the same reading for a sample on repeated testing, it is inferred that the measurement is
A. precise
B. accurate
C. specific
D. sensitive
A. precise
- Uncertainty between true value and observed value is
A. error
B. mistake
C. blunder
D. deviation
A. error
- The degree to which the instrument measures what it purports to measure is?
A. validity
B. reliability
C. accuracy
D. precision
A. validity