LE 1 - Contributions of Chemical Engineering in Pharmaceutical Industry Flashcards
The discovery, development, and manufacture of drugs and medications (pharmaceuticals) by public and private organizations
Pharmaceutical Industry
Paracelsus advocated the use of chemistry to study the preparation of medicines
16th century
the first pharmacopoeia, or collected list of drugs and medicinal chemical with directions for making pharmaceutical preparations
1546
collected list of drugs and medicinal chemical with directions for making pharmaceutical preparations
pharmacopoeia
society of apothecaries was founded in London
1617
english physician and botanist William Withering published his famous monograph on the use of digitalis
1783
an extract from the flowering purple foxglove
digitalis
active ingredient, morphine, was isolated from opium
1804
quinine was isolated from cinchona bark and colchicine from autumn crocus
1820
malaria treatment
quinine
gout treatment
colchicine
atropine was purified from atropa belladonna
1833
pharmaceutical society of great britain was founded
1841
cocaine was isolated from cocoa leaves
1860
british surgeon and medical scientist Joseph Lister initiated the era of antiseptic surgery in England
1865
development of rabies vaccine by the French chemist and microbiologist Louis Pasteur
1885
number of important new classes of pharmaceutical were developed such as chloral hydrate, salicylic acid, etc.
late 19th century
arsphenamine was developed by German medical scientist Peul Ehrlich for the treatment of syphilis until 1940s when it was replaced by penicillin
1910
it was shown that certain azo dyes, which contained sulfonamide groups, known and Prontosil, were effective in treating streptococcal infections in mice
1930s
most of the world’s largest pharmaceutical companies were located in chuchu
20th century-present
Chemical Engineers in Pharmaceutical Industry
- Robert Langer
- Nicolas A. Peppas
- David A. Edwards
- Kim Sang Tae
Pioneer of many new technologies, including the controlled system and transdermal delivery system
Robert Langer
Leading researcher, inventor and pacesetter in the field of drug delivery and controlled release.
Nicolas A. Peppas
Research and development of advanced new drug delivery platforms for treating infectious diseases
David A. Edwards