LC U3 SPECIALIZED CT Flashcards
consists of formed elements and fluid component
Blood
Formed elements and fluid component of blood
Formed elements : erythrocytes, leukocytes, platelets
Fluid component : Plasma
average volume of blood in an average adult
5L of blood that moves unidirectionally within the closed circulatory system
Functions of blood
- transports
- regulates body temperature
- assists in the regulation of osmotic and acid-base balance
- immune defense
- clot formation
what is a buffy coat
- thin gray-white layer
- between plasma and hematocrit
- consists of leukocytes and platelets
difference of plasma and serum
Serum - pale yellow liquid
Plasma - straw-colored, translucent; found in blood with anticoagulant
role of blood to hormone distribution
permits the exchange of chemical messages between distant organs regulating normal organ function
body’s chief defenses against infection
Leukocytes
dissolved components in plasma
- Plasma proteins
- Respiratory gases
- Nitrogenous waste products
- Hormones
- Electrolytes
5 main plasma proteins
- Albumin
- Y-Globulin
- A and b-globulins
- Fibrinogen
- Complement proteins
most abundant plasma protein made in the liver
Albumin
preserves osmotic pressure and helps transport some metabolites
Albumin
secreted by plasma cells in many locations and are also called as antibodies
Y-Globulin
made by the livers and other cells and also transport metal ions and lipids
Globulins (a & b-globulins)
clotting proteins and converted into fibrin during blood clotting
Fibrinogen
largest plasma protein
Fibrinogen
defensive system important in inflammation and destruction of microorganism
Complement proteins
proteins serve to buffer against pH changes
Plasma proteins
stains used for blood smears
Eosin and methylene blue
general features of erythrocytes
anucleated, has hemoglobin, and is biconcave shaped
skeletal proteins that contribute to mechanical support of plasma membranes
Ankyrin
life span of erythrocytes
approximately 120 days
estimation of volume packed RBCs per unit volume of blood
Hematocrit
composed of four polypeptide chains covalently linked to a heme group
Hemoglobin
best-known membrane of any cell
Erythrocyte plasmalemma
contains varying amount of azurophilic granules
Leukocytes
general features of leukocytes
- spherical nucleated cells
- migrate to tissues to perform various activities
two groups of leukocytes
- Granulocytes
- Agranulocytes
two types of granulocytes
- Azurophilic Granules
- Specific Granules
Types of Agranulocytes
Lymphocytes and Monocytes
Types of Granulocytes
Neutrophils, Eosinophils and Basophils
Functions of Neutrophils
kills and phagocytose bacteria
Functions of Eosinophils
kills parasites and modulates local inflammation
Functions of Basophils
modulates inflammation and releases histamine during allergy
Functions of Lymphocytes
effector and regulatory cells for adaptive immunity
Functions of Monocytes
precursors of macrophages and other mononuclear phagocytic cells