Laxatives/Purgatives

Question 1

Laxatives / Purgative

Answer 1

Drugs that promote defecation by reducing the viscosity of the content of lower colon

Question 2

Clinical uses of laxatives

Answer 2

Constipation
Before : bowel surgery
delivery
Some investigation
Xray abdomen
Colonoscopy
Ultrasonography

Question 3

Causes of constipation

Answer 3

Functional & habitual
Prolong redress
Painful anal fissure
Hemorrhoids
Elderly patient
Bed retained patient
Drugs – morphine
Anticholinergic.
Antihistamine
Ca+2 channel blocker
Benzodiazepin
Iron tablets

Question 4

Bulk forming laxatives

Answer 4

Isapgula husk
Methylcellulose
Bran

Question 5

Stimulant

Answer 5

Senna
Bisacodyl
Sodium picosulfate
Glycerine suppositories

Question 6

Osmotic laxatives

Answer 6

Lactose
Magnesium sulphate
Phosphate enema

Question 7

Faecal softeners

Answer 7

Docusate sodium
Liquid paraffin
Arachis oil

Question 8

Prokinetic agents

Answer 8

Prucalopride
Tegaserod

Question 9

Adverse effects of laxatives

Answer 9

Diarrhoea
Nutritional deficiency
Electrolyte imbalance
Atonic colon
Vitamin deficiency
Abdominal cramps

Question 10

Contraindications

Answer 10

1.Undiagnosed acute abdominal pain
2. Intestinal obstruction
3. Peritonitis
4. Acute appendicitis
5. Pregnancy

Question 11

Use of lactolose

Answer 11

In chronic liver disease to prevent hepatic encephalopathy
As a laxa5in constipation and anal fissure