Anti Anginal

Question 1

Patients complain

Answer 1

1. Constricting pain over the chest
2. Short lasting pain 5 10min
3. Radiating pain( left shoulder)
4. Pain relived by rest

Question 2

Myocardial O2 consumption depends on

Answer 2

Heart rate
Preload
After load
Cardiac contractility

Question 3

Treatment objective of angina

Answer 3

Improves myocardial perfusion
Dec the need of oxygen
By : stopping of provocative exercise
Dec Preload = end diastolic volume
Dec aft load
Dec heart rate

Question 4

Types of angina

Answer 4

Classical angina (stable angina) - atherosclerosis l
Variant / prinzmetal angina - vasospasam
Unstable angina - progressive occlusion
Rupture of athromatous plaque & platelet aggregation at ruptured plaque

Question 5

Organic nitrates and nitrites

Answer 5

Short acting : nitroglycerin, isosorbide dinitrate( sublingual)
Amyl nitrate (inhalant)
Long acting : nitroglycerin oral sustained tablet, isosorbide dinitrate and mononitrate, nitroglycerin transdermal patch