Haematinics Flashcards

1
Q

Define haematinics

A

Agents that causes stimulation of haemopoiesis
Which results in correction of anaemia

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2
Q

Causes of anaemia

A

1.Blood loss
2. Impaired RBC production due to. deficiency of essential factor .bone marrow. depression ,erythropoetin deficiency
3. Incresed destruction of RBC

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3
Q

Factor increses iron Absorption

A
  1. Acid: dissolution and reduction of ferric to ferous in stomach by influence of gastric hcl
  2. Reducing substances : ascorbic acid and amino acid
  3. Individual with iron deficiency
  4. Vitamin C increases Absorption
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4
Q

Factor decreases iron Absorption

A
  1. Alkali makes iron insoluble
  2. Phosphate ,tetracycline - by complexing with iron
  3. Presence of other food in stomach
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5
Q

Iron preparation
Oral tablets ,syrup

A
  1. Ferrous sulphate
  2. Ferrous gluconate
  3. Ferrous succinate
  4. Ferrous fumarate
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6
Q

Parenteral iron

A
  1. Iron dextran
  2. Iron sorbital
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7
Q

Indication of parenteral Iron therapy

A
  1. Oral iron not tolerated
  2. Failure to absorb Oral iron due to malabsorption ,inflammation due to rheumatoid arthritis
  3. non compliances
  4. In presence of severe deficiency with chronic bleeding
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8
Q

Drug Interaction

A

Iron +tetracycline
Iron+ methyldopa
Iron + ciprofloxacin
Iron+ antacid

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