Haematinics Flashcards
1
Q
Define haematinics
A
Agents that causes stimulation of haemopoiesis
Which results in correction of anaemia
2
Q
Causes of anaemia
A
1.Blood loss
2. Impaired RBC production due to. deficiency of essential factor .bone marrow. depression ,erythropoetin deficiency
3. Incresed destruction of RBC
3
Q
Factor increses iron Absorption
A
- Acid: dissolution and reduction of ferric to ferous in stomach by influence of gastric hcl
- Reducing substances : ascorbic acid and amino acid
- Individual with iron deficiency
- Vitamin C increases Absorption
4
Q
Factor decreases iron Absorption
A
- Alkali makes iron insoluble
- Phosphate ,tetracycline - by complexing with iron
- Presence of other food in stomach
5
Q
Iron preparation
Oral tablets ,syrup
A
- Ferrous sulphate
- Ferrous gluconate
- Ferrous succinate
- Ferrous fumarate
6
Q
Parenteral iron
A
- Iron dextran
- Iron sorbital
7
Q
Indication of parenteral Iron therapy
A
- Oral iron not tolerated
- Failure to absorb Oral iron due to malabsorption ,inflammation due to rheumatoid arthritis
- non compliances
- In presence of severe deficiency with chronic bleeding
8
Q
Drug Interaction
A
Iron +tetracycline
Iron+ methyldopa
Iron + ciprofloxacin
Iron+ antacid