LAS 3

Question 1

this adds necessary bulk to a formulation to prepare tablets of the desired size

Answer 1

Diluents, fillers

Question 2

promote adhesion to the particles of the formulation

Answer 2

adhesives

Question 3

promote breakup of the tablets after administration to smaller particles

Answer 3

disintegrants

Question 4

enhance the flow of the material into tablet dies and etc.

Answer 4

lubricants

Question 5

what are the parts of tablet press

Answer 5

Hopper
feed frame
dies
punches
cam

Question 6

this stores the material for compression

Answer 6

hopper

Question 7

this distributes the material into the dies

Answer 7

feed frame

Question 8

this controls the size and shape of the tablets

Answer 8

dies

Question 9

this compacts the materials within the dies

Answer 9

punches

Question 10

this is for guiding and punches

Answer 10

cams

Question 11

what are the ingredients used in acetaminophen formulation?

Answer 11

acetaminophen (516.24), starch (6.2), magnesium stearate (6.2), talcum (6.2), methylparaben sodium (.11), propylparaben sodium (.02)

Question 12

what is the title of the LAS 3 activity?

Answer 12

Preparation of Acetaminophen tablets

Question 13

what is procedure 1?

Answer 13

weight the exact amount of ingredients

Question 14

what is procedure 2?

Answer 14

blend the powders in a mortar and pestle by trituration (adding gelatin last)

Question 15

what is procedure 3?

Answer 15

Add 1ml of distilled water in portions then blend

Question 16

what is procedure 4?

Answer 16

compress the granules into tablets through tableting machine

Question 17

what is procedure 5?

Answer 17

conduct quality control test

Question 18

what are the quality control tests specified in the LAS 3 activity?

Answer 18

Tablet weight and tablet variation
Tablet thickness
Tablet friability