Large Animal NSAIDs Flashcards
which NSAIDs are available in cattle (including extralabel)?
aspirin
flunixin
meloxicam
ketoprofen
what are the main adverse effects of NSAIDs in horses?
renal papillary necrosis
gastrointestinal toxicity
what is the first choice for colic, general peri-operative analgesia/anti-inflammatory, and endotoxemia?
flunixin
what dose is used for endotoxemia of flunixin?
0.25 mg/kg q8h
0.5 mg/kg q12h
when does peak response from flunixin occur?
12-16 hours
duration 24-36 hours
how does phenylbutazone compare to flunixin?
more effective for musculoskeletal pain
what is the most toxic NSAID in horses?
phenylbutazone
what is firocoxib used primarily for?
chronic osteoarthritis
what is dipyrone labeled for?
pyrexia
also used for spasmodic colic
can you use dipyrone in food animals?
no
should you use NSAIDs in foals?
no
what are the best NSAIDs for acute musculoskeletal disease?
phenylbutazone
ketoprofen (meloxicam)
which NSAIDs should you not use off-label in cattle?
phenylbutazone
carprofen
dipyrone
firocoxib
ibuprofen
which NSAIDs can be used in lactating diary cows?
flunixin (two forms)
can you use meloxicam in cattle?
extralabel
what dose is flunixin used at in horses?
0.25 mg/kg q8h or 0.5 mg/kg q12h
what is the duration of flunixin?
24-36 hours
what can phenylbutazone cause?
right dorsal colitis
renal papillary necrosis
what is firocoxib used primarily for?
chronic osteoarthritis
what is the half life of firocoxib?
30-40 hours
11 hours in foals
what dipyrone used for?
pyrexia
spasmodic colic
which drug should you use a loading dose of for rapid onset?
firocoxib
which drug is approved for mastitis in bovine?
flunixin
which NSAIDs cannot be used in lactating dairy cows?
aspirin
ketoprofen
meloxicam