Large Animal NSAIDs Flashcards

1
Q

which NSAIDs are available in cattle (including extralabel)?

A

aspirin
flunixin
meloxicam
ketoprofen

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2
Q

what are the main adverse effects of NSAIDs in horses?

A

renal papillary necrosis
gastrointestinal toxicity

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3
Q

what is the first choice for colic, general peri-operative analgesia/anti-inflammatory, and endotoxemia?

A

flunixin

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4
Q

what dose is used for endotoxemia of flunixin?

A

0.25 mg/kg q8h
0.5 mg/kg q12h

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5
Q

when does peak response from flunixin occur?

A

12-16 hours
duration 24-36 hours

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6
Q

how does phenylbutazone compare to flunixin?

A

more effective for musculoskeletal pain

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7
Q

what is the most toxic NSAID in horses?

A

phenylbutazone

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8
Q

what is firocoxib used primarily for?

A

chronic osteoarthritis

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9
Q

what is dipyrone labeled for?

A

pyrexia
also used for spasmodic colic

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10
Q

can you use dipyrone in food animals?

A

no

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11
Q

should you use NSAIDs in foals?

A

no

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12
Q

what are the best NSAIDs for acute musculoskeletal disease?

A

phenylbutazone
ketoprofen (meloxicam)

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13
Q

which NSAIDs should you not use off-label in cattle?

A

phenylbutazone
carprofen
dipyrone
firocoxib
ibuprofen

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14
Q

which NSAIDs can be used in lactating diary cows?

A

flunixin (two forms)

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15
Q

can you use meloxicam in cattle?

A

extralabel

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16
Q

what dose is flunixin used at in horses?

A

0.25 mg/kg q8h or 0.5 mg/kg q12h

17
Q

what is the duration of flunixin?

A

24-36 hours

18
Q

what can phenylbutazone cause?

A

right dorsal colitis
renal papillary necrosis

19
Q

what is firocoxib used primarily for?

A

chronic osteoarthritis

20
Q

what is the half life of firocoxib?

A

30-40 hours
11 hours in foals

21
Q

what dipyrone used for?

A

pyrexia
spasmodic colic

22
Q

which drug should you use a loading dose of for rapid onset?

A

firocoxib

23
Q

which drug is approved for mastitis in bovine?

A

flunixin

24
Q

which NSAIDs cannot be used in lactating dairy cows?

A

aspirin
ketoprofen
meloxicam

25
Q

what can meloxicam be used extra-label for in cattle?

A

calf diarrhea
de-budding
acute mastitis
post-op
castration

26
Q

when can you not use meloxicam in cattle?

A

not approved for beef or dairy

27
Q

what is flunixin transdermal labeled for?

A

footrot
control fever in bovine respiratory disease
control fever due to mastitis

28
Q

are there approved products for dehorning and castration in the US?

A

no

29
Q

which NSAID is approved for us in cattle as a stand-alone NSAID?

A

flunixin- only
ketoprofen only in combination