Large Animal NSAIDs Flashcards

1
Q

which NSAIDs are available in cattle (including extralabel)?

A

aspirin
flunixin
meloxicam
ketoprofen

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2
Q

what are the main adverse effects of NSAIDs in horses?

A

renal papillary necrosis
gastrointestinal toxicity

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3
Q

what is the first choice for colic, general peri-operative analgesia/anti-inflammatory, and endotoxemia?

A

flunixin

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4
Q

what dose is used for endotoxemia of flunixin?

A

0.25 mg/kg q8h
0.5 mg/kg q12h

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5
Q

when does peak response from flunixin occur?

A

12-16 hours
duration 24-36 hours

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6
Q

how does phenylbutazone compare to flunixin?

A

more effective for musculoskeletal pain

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7
Q

what is the most toxic NSAID in horses?

A

phenylbutazone

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8
Q

what is firocoxib used primarily for?

A

chronic osteoarthritis

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9
Q

what is dipyrone labeled for?

A

pyrexia
also used for spasmodic colic

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10
Q

can you use dipyrone in food animals?

A

no

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11
Q

should you use NSAIDs in foals?

A

no

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12
Q

what are the best NSAIDs for acute musculoskeletal disease?

A

phenylbutazone
ketoprofen (meloxicam)

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13
Q

which NSAIDs should you not use off-label in cattle?

A

phenylbutazone
carprofen
dipyrone
firocoxib
ibuprofen

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14
Q

which NSAIDs can be used in lactating diary cows?

A

flunixin (two forms)

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15
Q

can you use meloxicam in cattle?

A

extralabel

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16
Q

what dose is flunixin used at in horses?

A

0.25 mg/kg q8h or 0.5 mg/kg q12h

17
Q

what is the duration of flunixin?

A

24-36 hours

18
Q

what can phenylbutazone cause?

A

right dorsal colitis
renal papillary necrosis

19
Q

what is firocoxib used primarily for?

A

chronic osteoarthritis

20
Q

what is the half life of firocoxib?

A

30-40 hours
11 hours in foals

21
Q

what dipyrone used for?

A

pyrexia
spasmodic colic

22
Q

which drug should you use a loading dose of for rapid onset?

23
Q

which drug is approved for mastitis in bovine?

24
Q

which NSAIDs cannot be used in lactating dairy cows?

A

aspirin
ketoprofen
meloxicam

25
what can meloxicam be used extra-label for in cattle?
calf diarrhea de-budding acute mastitis post-op castration
26
when can you not use meloxicam in cattle?
not approved for beef or dairy
27
what is flunixin transdermal labeled for?
footrot control fever in bovine respiratory disease control fever due to mastitis
28
are there approved products for dehorning and castration in the US?
no
29
which NSAID is approved for us in cattle as a stand-alone NSAID?
flunixin- only ketoprofen only in combination