Large animal models Flashcards

1
Q

Name advantages of using large animals as models

A
  • outbred
  • repeated blood samples possible
  • tissue biopsies
  • longer life-span
  • similar size to that of humans
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Name disadvantages of large animal models

A
  • outbred
  • expensive
  • limited number of animals for practical and economical reasons
  • handling can be cumbersome
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Where can you sample blood from pigs?

A
  • jugular vein
  • ear vein
  • mammary vein
  • retroorbital plexus
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Name three different pig/swine kinds

A
  • Yorkshire (pointy ears standing up)
  • Hampshire (belt)
  • landrace (ears hang down)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Why do you use minipigs for long-term studies?

A

They don’t grow that big

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are Göttingen minipigs bred from?

A

minnesota minipig + vietnamese pig + landrace

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the 3 As in pig research?

A
  • Acclimatisation
  • Analgesia and Anaesthesia
  • Aseptic procedures
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are dogs used for in research?

A
  • test new pharmaceuticals
  • toxicity - non-rodent model
  • surgery - transplantation
  • insulin 1920s breakthrough
  • Gi tract
  • new vaccines for dogs
  • dentistry
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Where are cat models used?

A
  • CNS
  • neurology
  • opthalmology
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Research on primates

A
  • HIV
  • transplantation
  • ophtalmology
  • PET
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Research areas that use rabbits

A
  • orthopedics
  • osseointegration
  • ophtalmology
  • antibody production
How well did you know this?
1
Not at all
2
3
4
5
Perfectly