Lameness in calves Flashcards
1
Q
Arthritis definition
A
- inflammation of joints (synovial membrane and articular surfaces)
2
Q
Septic arthritis definition
A
- arthritis due to infection
3
Q
Polyarthritis definition
A
- multiple joint affected
- septic or immune-mediated
4
Q
Septic arthritis aetiopathogenesis in calves <3w old
A
- FPT is primary risk factor
-> omphalophlebitis (mixed bacteria) or septicaemia (Gram-negatives)
-> circulating bacteraemia
-> bacteria localise on articular surfaces - polyarthritis is common
- calves might also show other CS related to sepsis e.g. meningitis, uveitis, enteritis
- prognosis = guarded to poor
- multiple joints = poorer prognosis
- FPT = poorer prognosis
5
Q
Septic arthritis aetiology calves >3w old
A
- may be subsequent to penetrating wounds (T.pyogenes - opportunistic bacteria seen in lots of cattle infections)
- Mycoplasma bovis: typically BRD also present +/- otitis media/interna (head tilt), often stifles affected
- circulating bacteraemia: intestinal origin e.g. Salmonella spp, respiratory origin e.g. H.somni, M.bovis
6
Q
Septic arthritis: diagnosis
A
- clinical exam and history
- arthrocentesis: clip & scrub area, large gauge needle (16G or 18G), sedate if needed, culture sample
- imaging: rarely done as rarely adds info on top of CE
7
Q
Septic arthritis presenting signs
A
- pain -> lameness (NWB if 1 leg affected)
- affected joints painful and hot to touch, more chronic cases might not be
- joint swelling variable -> pyogenic bacteria = greatest swelling
- general signs variable present e.g. pyrexia, inappetence, weight loss
- co-morbidities may be present: omphalophlebitis in young calves, endocarditis in older animals
- chronic: fibrin development -> will be swollen but less painful and may not be hot, less likely to see general signs
8
Q
Septic arthritis CE
A
- acute cases usually pyrexic and dull
- observe the calf walking: lameness will be present, keen to lie down
- if recumbent see if calf will stand: will be difficult or maybe not possible
- examine joints: usually painful, usually reduced RoM -> may be very impaired or ankylosed if chronic
- hock, stifle and carpus most commonly affected
- older calves -> often single joint affected
- young calves -> typically multiple joints
9
Q
PM finding of a septic arthritis joint
A
- lots of fibrin
- synovial fluid very turbid
- can see frank pus instead of synovial fluid
10
Q
Arthrocentesis of a septic arthritis joint
A
- volume: high
- ease of obtaining fluid: usually easy
- gross appearance: turbid, yellow, may be purulent, may be more watery/less viscous
- leukocytes µL: high numbers (4000-8000), predominantly neutrophils (80-90%)
- protein: high (TP = 3.2-4.5g/dL)
- microbiology: bacteria (or other pathogens) might be culture or visible on Diff Quid (although not always)
11
Q
Septic arthritis tx
A
- analgesia: NSAIDs
- antibiotics: select based on likely organisms, penicillin/oxytet/TMPS (parenteral, licensed, broad spec, penetrate synovial membrane), long course recommended (3w), intra-articular antibiotics (described but rarely used, no licensed formulation)
- joint lavage (+ antibiotics + NSAIDs): better results than antibiotics + NSAIDs alone
- supportive care: feeding, bedding, good nursing
12
Q
Septic arthritis likely pathogens
A
- Trueperella pyogenes
- Fusobacterium necophorum
- Staphylococcal spp
- E.coli
- Salmonella spp
- Mycoplasma bovis
- Erysipelothrix rhusiopathiae
13
Q
Trueperella pyogenes causing septic arthritis (presentation, common? antibiotic susceptibility)
A
- presentation: any age of calves, concurrent omphalophlebitis in calves <3w
- common? very common, the most common isolate in older calves and adults
- antibiotic susceptibility: penicillin, amoxicillin, oxygen, TMPS
14
Q
Fusobacterium necophorum causing septic arthritis (presentation, common? antibiotic susceptibility)
A
- presentation: any age of calves, concurrent omphalophlebitis in calves <3w, may also see calf diphtheria, faecally spread
- common? yes, esp if unhygienic feeding practices
- antibiotic susceptibility: amoxicillin, TMPS, oxytet
15
Q
Staphylococcal spp causing septic arthritis (presentation, common? antibiotic susceptibility)
A
- presentation: any age of calves, concurrent omphalophlebitis in calves <3w
- common? yes
- antibiotic susceptibility: penicillin, amoxicillin, oxytet, TMPS