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Therapuetics - Exam 3 > LAMA and ICS/LABA drugs > Flashcards

LAMA and ICS/LABA drugs Flashcards

1
Q

aclidinium brand

A

turdorza pressair

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2
Q

aclidinium (turdorza pressair) dosage form

A

400 mcg per inhalation

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3
Q

glycopyrrolate (seebri neohaler) dosage forms

A

DPI - 15.6 mcg capsule
Nebulization solution - 25 mcg/mL

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4
Q

glycopyrrolate brand

A

seebri neohaler

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5
Q

revefenacin brand

A

yupelri

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6
Q

revefenacin (yupelri) dosage form

A

nebulization solution
175 mcg (1 unit dose vial)

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7
Q

tiotropium brand

A

spiriva

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8
Q

tiotropium (spiriva) dosage forms

A

handihaler - 18 mcg capsule
respimat - 1.25 or 2.5 mcg/inhalation

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9
Q

umeclidinium brand

A

incruse ellipta

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10
Q

umeclidinium (incruse ellipta) dosage form

A

DPI
62.5 mcg/inhalation

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11
Q

aclidinium (turdorza pressair) dosing in adults

A

one inhalation bid
COPD only

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12
Q

glycopyrrolate (seebri neohaler) dosing in adults

A

DPI - one capsule bid
Nebulization Solution - one vial bid
COPD only

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13
Q

revenfenacin (yupelri) dosing in adults

A

one nebulization qd
COPD only

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14
Q

tiotropium (spiriva) dosing in adults

A

handihaler - contents of one capsule qd (COPD only)
respimat - two inhalations qd

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15
Q

umeclidinium (incruse ellipta) dosing in adults

A

one inhalation qd
COPD only

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16
Q

tiotropium (spiriva) dosing in 4-11 yos

A

only approved in over 6 yos
respimat - two inhalations qd

17
Q

adverse effects of LAMAs

A

dry mouth
dizziness
blurred vision
upper respirator infections
paradoxical bronchospams

18
Q

clincial pearls of LAMA

A

tiotropium has been approved for use in asthma as an add-on option for children under 12 yos

19
Q

LAMAs

A

long acting antimuscarinics
block the bronchoconstrictor effects of acetylcholine on M3 and M2 receptors

20
Q

LAMA drugs

A

aclidinium (turdorza pressair)
glycopyrrolate (seebri neohaler)
revenfenacin (yupelri)
tiotropium (spiriva)
umeclidinium (incruse ellipta)

21
Q

ICS/LABA combo drugs

A

fluticasone/salmeterol (advair, AirDuo, AirDuo Digihaler)
budesonide/formoterol (symbicort)
mometasone/formoterol (dulera)
fluticasone/vilanterol (breo ellipta)

22
Q

fluticasone/salmeterol brands

A

advair
airduo
airduo digihaler

23
Q

budesonide/formoterol brand

24
Q

fluticasone salmeterol (advair) dosage forms

A

DPI - 100 mcg/50mcg, 250mcg/50mcg, and 500mcg/50mcg
HFA MDI - 45 mcg/21mcg, 114mcg/21mcg, and 230mcg/21mcg

25
Q

fluticasone/salmeterol (AirDuo and AirDuo Digihaler) dosage form

A

respiclick (DPI)
55mcg/14 mcg
113mcg/14 mcg
232mcg/14 mcg

26
Q

budesonide/formoterol (symbicort) dosage form

A

HFA MDI
80 mcg/4.5 mcg
160 mcg/4.5 mcg

27
Q

fluticasone/salmeterol (advair) dosing in adults

A

DPI - one inhalation bid
HFA - two inhalations bid

28
Q

fluticasone/salmeterol (advair) dosing in 5-11 yos

A

over 4 yos
DPI only
two inhalation bid of 100mcg/50mcg product

29
Q

fluticasone/salmeterol (airduo, airduo digihaler) dosing in adults

A

one inhalation bid

30
Q

budesonide/formoterol (symbicort) dosing in adults

A

two inhalations bid

31
Q

budesonide/formoterol (symbicort) dosing in 5-11 yos

A

two inhalations bid

32
Q

ICS/LABA combo adverse effects

A

individual product’s profile

33
Q

clinical pearls of ICS/LABA combos

A

guidelines recommend combination LABA with ICS in asthma, as LABA should not be used as a monotherapy
combination products developed to create convenient packaging and assist with patient adherence

34
Q

mometasone/formoterol brand

35
Q

mometasone/formoterol (dulera) dosage form

A

MDI
100mcg/5mcg
200mcg/5mcg

36
Q

fluticasone/vilanterol brand

A

breo ellipta

37
Q

fluticasone/vilanterol (breo ellipta) dosage form

A

DPI
100 mcg/5 mcg
200 mcg/ 25 mcg

38
Q

mometasone/formoterol (dulera) dosing in adults

A

two inhalations bid

39
Q

fluticasone/vilanterol (breo ellipta) dosing in adults

A

one inhalation qd

Therapuetics - Exam 3 (12 decks)

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