LABA/LAMA combo, LABA/LAMA/ICS combo, and mast cell stabilizer

Question 1

olodaterol/tiotropium brand

Answer 1

stiolto respimat

Question 2

olodaterol/tiotropium (stiolto respimat) dosage form

Answer 2

respimat
2.5 mcg/2.5mcg/inhalation

Question 3

vilanterol/umeclidinium brand

Answer 3

anoro ellipta

Question 4

vilanterol/umeclidinium (anoro ellipta) dosage form

Answer 4

ellipta
62.5mcg/25mcg/inhalation

Question 5

indacaterol/glycopyrronium brand

Answer 5

utibron neohaler

Question 6

indacaterol/glycopyrronium (utibron neohaler) dosage form

Answer 6

neohaler
27.5mcg/15.6mcg capsules

Question 7

formoterol/glycopyrronium brand

Answer 7

bevespi aerosphere

Question 8

formoterol/glycopyrronium (bevespi aerosphere) dosage form

Answer 8

aerosphere
4.8mcg/9mcg/inhalation

Question 9

formoterol/aclidinium brand

Answer 9

duaklir pressair

Question 10

formoterol/aclidinium (duaklir pressair) dosage form

Answer 10

DPI
12mcg/400mcg/actuation

Question 11

olodaterol/tiotropium (stiolto respimat) dosing in adults

Answer 11

two inhalations qd
COPD only

Question 12

vilanterol/umeclidinium (anoro ellipta) dosing in adults

Answer 12

one inhalation qd
COPD only

Question 13

indacaterol/glycopyrronium (utibron neohaler)

Answer 13

contents of one capsule bid
COPD only

Question 14

clinical pearls of LABA/LAMA combo

Answer 14

see individual products for side effect profile
not indicated for treatment of acute deteriorations
COPD only

Question 15

formoterol/glycopyrronium (bevespi aerosphere) dosing in adults

Answer 15

two inhalations BID
COPD only

Question 16

formoterol/aclidinium (duaklir pressair) dosing in adults

Answer 16

one inhalation bid
COPD only

Question 17

LABA/LAMA combos

Answer 17

olodaterol/tiotropium (stiolto respimat)
vilanterol/umeclidinium (anoro ellipta)
indacaterol/glycopyrronium (utibron neohaler)
formoterol/glycopyrronium (bevespi aerosphere)
formoterol/aclidinium (duaklir pressair)

Question 18

LABA/LAMA/ICS combos

Answer 18

fluticasone/umeclidinium/vilanterol (trelegy ellipta)
budesonide/glycopyrrolate/formoterol fumarate (breztri aerosphere)

Question 19

fluticasone/umeclidinium/vilanterol brand

Answer 19

trelegy ellipta

Question 20

fluticasone/umeclidinium/vilanterol (trelegy ellipta) dosage form

Answer 20

ellipta
100-62.5-25mcg/inhalation
200-62.5-25mcg/inhalation

Question 21

budesonide/glycopyrrolate/formoterol fumarate brand

Answer 21

breztri aerosphere

Question 22

budesonide/glycopyrrolate/formoterol fumarate (breztri aerosphere) dosage form

Answer 22

aerosphere
160mcg/9mcg/4.8mcg/inhalation

Question 23

fluticasone/umelcidinium/vilanterol (trelegy ellipta) dosing in adults

Answer 23

asthma - one inhalation qd (two available doses)
COPD - one inhalation qd (only lower dose)

Question 24

budesonide/glycopyrrolate/formoterol fumarate (breztri aerosphere) dosing in adults

Answer 24

two inhalations bid
COPD only

Question 25

adverse effects of LABA/LAMA/ICS combo

Answer 25

see individual products

Question 26

cromolyn brand

Answer 26

intal

Question 27

cromolyn (intal) dosage form

Answer 27

nebulizer solution
20mg/ampule

Question 28

cromolyn (intal) dosing in 0-4 yos

Answer 28

one ampule qid
safety/efficacy not established in children under 2 yos

Question 29

cromolyn (intal) dosing in 5-11 yos

Answer 29

one ampule qid

Question 30

cromolyn (intal) dosing in adults

Answer 30

one ampule qid

Question 31

mast cell stabalizer

Answer 31

cromolyn (intal)

Question 32

adverse effects of cromolyn (intal)

Answer 32

high incidence of unpleasant taste in mouth (over 10%)
rare cardiac arrhythmias
coughing
dyspnea
sore throat
nausea, vomiting, diarrhea if absorbed systemically

Question 33

clinical pearls of cromolyn (intal)

Answer 33

less effective than low-dose ICS
prevents increase in bronchial hyperreactivity seen in allergy season