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Therapuetics - Exam 3 > ICS and LABA only drugs > Flashcards

ICS and LABA only drugs Flashcards

1
Q

beclomethasone brand

A

QVAR

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2
Q

beclomethasone (qvar) dosage form

A

redihaler (mdi)
40 or 80 mcg/inhalation

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3
Q

ciclesonide brand

A

alvesco

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4
Q

beclomethasone (qvar) dosing in 5-11 yos

A

40-80 mcg inhaled bid

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5
Q

beclomethasone (qvar) dosing in adults

A

40-320 mcg inhaled bid

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5
Q

budesonide brand

A

pulmicort
pulmicort respules

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5
Q

budesonide (pulmicort) dosage form

A

flexhaler
90 or 180 mcg/inhalation

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5
Q

budesonide (pulmicort) dosing in 5-11 yos

A

90-360 mcg inhaled bid

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6
Q

budesonide (pulmicort) dosing in adults

A

90-720 mcg inhaled bid

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7
Q

budesonide (pulmicort respules) dosage form

A

nebulizer solution
0.25mg/2mL
0.5mg/2mL
1mg/2mL

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8
Q

ciclesonide (alvesco) dosage form

A

HFA
80 or 160 mcg/inhalation

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9
Q

fluticasone propionate brand

A

flovent
armonAir diginhaler

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10
Q

fluticasone propionate (flovent, armonair diginhaler) dosage form

A

HFA - 44, 110, or 220 mcg/inhalation
DPI - 50, 100, or 250 mcg/inhalation
aerosol powder inhaler - 55, 113, 232 mcg/actuation

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11
Q

fluticasone propionate (flovent, ArmonAir Diginhaler) dosing in 0-4 yos

A

only over 4 yos
HFA - 88 mcg bid
DPI - 50 mcg bid

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12
Q

budesonide (pulmicort respules) dosing in 0-4 yos

A

0.25 to 1 mg/day qd or divided bid

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13
Q

budesonide (pulmicort respules) dosing in 5-11 yos

A

0.5 to 2 mg per day qd or divided bid

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14
Q

ciclesonide (alvesco) dosing in 5-11 yos

A

only over 6 yos
80 to 160 mcg qd

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15
Q

fluticasone propionate (flovent, armonair diginhaler) dosing in 5-11 yos

A

HFA - 44 to 88 mcg inhaled bid
DPI - 50 to 100 mcg inhaled bid

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16
Q

fluticasone propionate (flovent, armonair diginhaler) dosing in adults

A

HFA - 44 to 220 mcg inhaled bid
DPI - 50 to 250 mcg inhaled bid
MDPI - 55 to 232 mcg inhaled bid

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17
Q

ciclesonide (alvesco) dosing in adults

A

80 to 320 mcg inhaled bid

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18
Q

fluticasone furoate brand

A

arnuity ellipta

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19
Q

fluticasone furoate (arnuity ellipta) dosage form

A

50, 100, and 200 mcg per inhalation

20
Q

mometasone (asmanex) dosage forms

A

HFA - 50, 100, and 200 mcg/inhalation
twisthaler - 110 and 220 mcg/inhalation

21
Q

mometasone brand

22
Q

fluticasone fuorate (arnuity ellipta) dosing in 4-11 yos

23
Q

fluticasone fuorate (arnuity ellipta) dosing in adults

A

100 to 200 mcg inhaled qd

24
Q

mometasone (asmanex) dosing in 4-11 yos

A

HFA - 100 mcg bid
Twisthaler - 110 mcg qpm

25
Q

mometasone (asmanex) dosing in adults

A

HFA - 200 to 400 mcg bid
twisthaler - 110 to 880 mcg qpm

26
Q

inhaled corticosteroids (ICS) usage

A

prevent and control inflammation in asthma and COPD

27
Q

inhaled corticosteroids (ICS) medications

A

beclomethasone (qvar)
budesonide (pulmicort, pulmicort respules)
ciclesonide (alvesco)
fluticasone propionate (flovent, armonair diginhaler)
fluticasone fuorate (arnuity ellipta)
mometasone (asmanex)

28
Q

adverse effects of ICS

A

oral thrush (candidiasis)
cough
dysphonia

29
Q

counseling tip of ICS

A

patients should rinse their mouth and spit after use to prevent oral thrush

30
Q

clinical pearls of ICS

A

1) most effective long-term control therapy for asthma (improve quality of life, increase lung function, and reduce the risk of exacerbations)
2) may increase the risk of pneumonia in patients with COPD
3) titrate to lowest effective dose
4) pulmicort respules should use jet nebulizer and should not be mixed with other nebulizer medications
5) high doses increase the risk for systemic side effects

31
Q

arformoterol tartrate brand

32
Q

arformoterol tartrate (brovana) dosage form

A

nebulizer solution
15 mcg/2mL

33
Q

formoterol brand

A

perforomist

34
Q

formoterol (perforomist) dosage form

A

nebulizer solution
20 mcg/2mL

35
Q

indacaterol brand

A

arcapata neohaler

36
Q

indacaterol (arcapata neohaler) dosage form

A

neohaler
75 mcg per capsule

37
Q

olodaterol brand

A

striverdi respimat

38
Q

olodaterol (striverdi respimat) dosage form

A

respimate
2.5 mcg per inhalation

39
Q

arformoterol tartrate (brovana) dosing in adults

A

15 mcg inhaled bid
COPD only

40
Q

formoterol (perforomist) dosing in adults

A

20 mcg inhaled bid
COPD only unless used in combination with ICS in asthma

41
Q

indacaterol (arcapta neohaler) dosing in adults

A

75 to 300 mcg inhaled qd
COPD only

42
Q

olodaterol (striverdi respimat) dosing in adults

A

5 mcg (two inhalations) qd
COPD only

43
Q

salmeterol brand

44
Q

salmeterol (serevent) dosage form

A

diskus
50 mcg/blister

45
Q

salmeterol (serevent) dosing in 4-11 yos

A

inhale contents of one blister (50 mcg) bid

46
Q

salmeterol (serevent) dosing in adults

A

50 mcg (one blister) inhaled bid

47
Q

adverse effects of LABA

A

tachycardia
headache
tremor hypokalemia

48
Q

box warning for LABA

A

increased risk of asthma related death for all monotherapy LABA use (should not be used alone for asthma management)
increasing hospitalizations in pediatric and adolescent patients

49
Q

clinical pearls of LABAs

A

prolonged QT seen with intentional overdoses
not for acute symptoms
may be helpful for exercise induce bronchospasm
formoterol and indacaterol capsules should not be taken orall

50
Q

pediatric considerations of LABAs

A

most children under 4 yos cannot provide sufficient inspiratory flow for adequate lung delivering with a DPI

51
Q

LABA

A

long acting beta agonists
increased cAMP
bronchial smooth muscle relaxation and inhibit hypersensitivity mediators from mast cells (histamine and leukotrienes)

Therapuetics - Exam 3 (12 decks)

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