Labour Flashcards
What are the boundaries of the pelvic inlet?
anterior = superior pubic rami and upper margin of pubic symphysislateral = iliopectineal lines on each sideposterior = sacral promontory
What occurs in cervical ripening?
decreased collagen productionincreased glycosaminoglycansdecreased aggregation of collagen fibresincrease in inflammatory cells, triggered by prostaglandin production
What must changes must occur in the uterine smooth muscle to facilitate pregnancy?
- cell hypertrophy- increase in glycogen deposition- contractions occur to condition the muscle
What controls uterine smooth muscle contractions?
- oxytocin (increases frequency of action potentials)- prostaglandins (increase in Ca2+ release from intracellular stores)
How are contractions initiated?
Spontaneous depolarisation from pacemakers cells. Depolarisation spreads to each cell via specialised gap junction for coordinated contraction.
What controls the rate of production of prostaglandins?
progesterone to oestrogen ratioincreased P:O ratio causes decreased prostaglandin secretiondecrease P:O ration cause increased prostaglandin synthesis
Describe the Ferguson Reflex
increased stretching in the cervix and vagina causes afferent impulses to be sent to the brain and the hypothalamus stimulates massive oxytocin release from the posterior pituitary, which increases the frequency of the action potentials firing which stimulate the muscle contraction.
What changes occur in the cervix at the start of labour?
- thinning and flattening of cervix- Ferguson reflex- dilation of cervix starts- amnion ruptures
What stages must the fetus go through in order to be delivered?
- head flexes as it reaches the pelvic floor- head internally rotates- flexed head stretches vagina and perineum - head is delivered- head rotates and extends- shoulders rotate to follow the head- shoulders are delivered, followed by the rest of the body
What happens in the third stage of labour?
uterine contractions greatly increase to shear off the placenta and position it in the upper part of the vagina/lower uterine segment. they are expelled within 10 mins
What does the contraction of the uterus in the third stage of labour facilitate?
closes blood vessels and prevents significant bleeding.
What facilitates the strong uterine contraction at the end of the third stage of labour?
an oxytocic drug
Describe how the lungs are established in the newborn
1st breath expends the lungs and reorganises the pulmonary system. blood vessels stretch, so it is easier for them to travel through. have a dramatic decrease in pul. vascular resistance and pulmonary arterial pressure. also LA pressure rises to higher than RA pressure, which closes the foramen ovale.
How is the foramen ovale closed?
reversal of blood flow when LA pressure rises to higher than RA pressure
How is the ductus arteriosus closed?
SM in wall of DA is sensitive to pO2. when the massive increase occurs, this stimulates the smooth muscle to contract. the blood that enters the liver must now pass through the hepatic sinusoids.