Labor & Delivery Flashcards
How long is an ovulated egg viable in the ampulla?
18-24 hours
How long are sperm viable in the ampulla?
48-72 hours
When does implantation of a fertilized egg occur?
5-7 days after fertilization
When does hCG secretion begin after fertilization?
7-8 days after fertilization
What is the process of implantation?
- Apposition (blastocyst differentiates, placenta formed)
- Adhesion (binds to endometrium)
- Invasion (cells invade endometrium and establishes a blood supply)
Does the placenta belong to mother or fetus?
Fetus
How long does the corpus luteum produce progesterone in pregnancy?
First 7-9 weeks of pregnancy
Functions of placenta
- Exchange of O2 and CO2
- Waste removal
- Nutrients
- Produces hCG
Amount of hCG in early pregnancy
- Amount doubles every 2 days until 10 weeks gestation
- If NOT, the pregnancy may be compromised
GI changes in pregnancy
- Slowed emptying
- Increased acidity
Renal changes in pregnancy
- GFR increases by 50%
- Cr is lower than normal (hydration change, 0.33-0.59)
- Hydronephrosis in late pregnancy
Cardiac changes in pregnancy
- Blood volume increases 50%
- HCT falls until about 28 wks
- Increase in clotting factors
What is Naegele’s rule?
- Estimated due date
- Add 7 days to the 1st day of LMP
- Subtract 3 months
- Add 1 year
How is gestation divided?
- Trimester 1: 1-12 weeks
- Trimester 2: 13-27 weeks
- Trimester 3: 28-40 (42) weeks
How can the 1st trimester be divided?
- Embryonic (organogenesis, most sensitive to teratogens)
- Fetal (8 wks after fertilization or 10 wks after onset of LMP)
When is the embryo most sensitive to teratogens?
Embryonic period of 1st trimester (2-10 weeks gestation)
What is the difference between gestational and conception age?
2 weeks!
-Gestational refers to weeks after LMP
Normal pregnancy is how many weeks gestational/conceptional?
- 40 weeks gestational (after LMP)
- 38 weeks conceptional
- But almost always referred to as gestational anyway
Define embryo
1-8 weeks gestation
Define fetus
After 8 weeks gestation
Define term
37 weeks or beyond
When is a fetus typically viable?
- 23 to 24 wks gestation
- 600 g or more weight
When does medical abortion (miscarriage) occur?
- Less than 20 weeks gestation
- Less than 500 g weight
Define preterm vs. premature
- Preterm is birth before 37 wks
- Premature is birth b/w 28-37 wks, weight 1000-2500 g
Define low birth weight
Full term but less than 2500 g weight
Define macrosomia
Large baby weighing more than 4500 g (9.9 lbs)
Define gravidity
Number of pregnancies (live or dead)
Define parity
Number of birth events of 20+ wks gestation OR 500+ g
Define elderly primigravida
1st pregnancy over 35 yo
Define nulligravida
No pregnancies
Define nullipara
No births
FPAL system
- Alternative to GPA system classifying pregnancies/births
- Full term births, Preterm births, Abortions, Living children
Why is folic acid given during pregnancy?
To prevent spina bifida
FDA pregnancy drug categories
- A: adequate, human studies have not shown increased risk
- B: animal studies have revealed no evidence of harm
- C: animal studies have shown adverse effect
- D: human studies have demonstrated a risk to fetus
- X: positive evidence of fetal abnormality
S/S of pregnancy
- Amenorrhea
- NV (as early as 2 wks, resolves typically 13-16 wks gestation)
- Breast changes
- Skin changes
- Pelvic organ changes