Lab Values Flashcards
What are lab values for?
Screening , diagnosis, monitoring
Factors that affect lab values
Age
Gender
Race
Pregnancy
Food ingestion
What is all included in CBC?
Complete blood count
RBC
Hgb
Hct
MCV
MCH
MCHC
RDW
Platelet
WBC
RBC
of Red blood cells
Hgb
O2 carrying protien
Hct
Packed volume of RBCs and, % of total volume
MCV
Cell size (normocytic,, macro and micro)
MCH
Amount of Hgb per cell
MCHC
HgB/ Hct per 100 mL/RBCs
RDW
Red cell distribution width
Platelet
of plot. Per cc/blood
WBC
of white cells per mL/blood
Normal ranges for RBC count?
3.89-5.40 M/uL
What is RBC count?
The number of circulating RBCs in 1 mm3 of blood
What kind of molecules does RBC contain?
Hemoglobin molecules
RBC indices :
MCV
RDW
MCH
MCHC
Normal lab levels of MCV
80-95 fL
Normal lab level of RDW
11-14.5%
Normal lab levels of MCH
27-31 pg
Normal lab levels of MCHC
32-36 g/dL
High RBC could indicate what?
Congestinital heart disease, severe chronic obstructive pulmonary disease, polycythemia Vera, severe dehydration
What could low RBC count indicate?
Anemia, hemoglobinopathy, cirrhosis, hemolytic anemia, hemorrhage, dietary deficiency, bone marrow failure, prosthetic valves, renal disease, normal pregnancy, rheumatoid arthritis, lymphoma, leukemia, Hodgkin disease
Normal ranges for hemoglobin ( Hgb or Hgb)
12-16 g/dL
What does hemoglobin (Hgb, Hb) tell us?
Measurement of the total amount of Hgb in the blood
What does high amount of hemoglobin (Hgb or Hb) indicate?
Erythrocytosis
Congenital heart disease
Severe COPD
Polycythemia Vera
Severe dehydration
What does low hemoglobin (Hgb or Hb) indicate?
Anemia
hemoglobinopathy
Cirrhosis
Hemolytic anemia
Hemorrhage
Dietary deficiency
Bone marrow failure
Prosthetic valves
Renal disease
Normal pregnancy
Rheumatoid arthritis
Lymphoma
Leukemia
Hodgkin disease
What are the normal level of hematocrit (Hct)
37.0-47.0%
What does lab draw hematocrit (Hct) give us ?
Indirect measurement of RBC number and volume
Hematocrit lab draw is part of what?
Routine testing and anemia evaluation
What is the critical values of hematocrit?
< 15% or > 60 %
What does high hematocrit indicate
Erthrocytosis
Congestional heart disease
Severe COPD
Polycythemia Vera
Severe dehydration
What does low hematocrit indicate
Anemia
Hemoglobinopathy
Cirrhosis
Hemolytic anemia
Hemorrhage
Dietary deficiency
Bone marrow failure
Prosthetic valves
Renal disease
Normal pregnancy
Rheumatoid arthritis
Lymphoma
Leukemia
Hodgkin disease
What is anemia
Decrease in number of RBCs (erythrocytes)
What are some causes of anemia?
Blood loss
Impaired RBC production
RBC destruction
Or combination of all 3
What are the classifications of anemia
Etiology **
Morphology **
What is the count the normal count of platelet (thrombocytes)
150.000
What is platelet count?
Actual count of the number of platelets (thrombocytes) per cubic milliner of blood
Where are thrombocytes formed?
Formed in bone marrow
What does high count of platelet indicate?
Malignant
Polycythemia vera
Post splenectomy syndromes
Rheumatoid arthritis
Iron deficiency anemia
What is the name for a high platelet count?
Thrombocytosis
A platelet counts that is greater than 1 million puts a person at risk for what?
Risk of clotting
What does a count greater than 600,000 be at risk for?
Potential problems
What does a low platelet count indicate?
Hypersplenism
Hemorrhage
Immune thrombocytopenia
Leukemia
Thrombotic thrombocytopenia
Graves’ disease
Inherited disorders
DIC
Pernicious anemia
Hemolytic anemia
Cancer
Chemotherapy
Infection
What is a name for low platelet count?
Thrombocytopenia
What could it mean when people have a platelet count below 50,000?
Significant bleeding
TOTAL WMCs (leukocytes) lab values
3.6-10.8 K/uL
What do the labs of total WMCs give us
Measurement of total WBC count
What is total WBCs apart of?
Routine testing on CBC
What is the white cell differential count?
Percentage of each type of leuokocyte present in the specimen
What does the high total WBC indicate?
Infection, inflammation, tissue necrosis, sepsis, leukemic neoplasia, trauma, stress, dehydration, thyroid storm
What is another name for high total WBCs?
Leukocytosis
What does low total WBCs indicate?
Bone marrow failure, chemo, radiation therapy, overwhelming infections, autoimmune disease
Another name for low total WBCs
Leukopenia
WBC differential
Measurement of percentage of each WBC type in the blood
Normal values of Neutrophils
50-70%
Normal values of lymphocytes
20-40%
Normal values of monocytes
2-8%
Normal values of eosinophils
1-4%