Lab interpretation Flashcards

1
Q

Blood is ___% body weight

A

6-8

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2
Q

Blood is __% plasma and __% formed elements

A

55

45

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3
Q

Women have __ L of blood and men have __ L

A

4.5-5.5

5-6

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4
Q

Plasma is __% water and __% proteins

A

92

7

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5
Q

Reticulocyte

A

Before erythrocyte, has a nucleus and when it loses it it becomes erythrocyte

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6
Q

RBC production is stimulated by..

A

Erythropoietin

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7
Q

Increased RBCs

A

Polycythemia

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8
Q

Decreased RBCs

A

Anemia

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9
Q

Life cycle of RBCs

A

120 days, 0.8% replaced daily

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10
Q

85% of RBCs are recycled by…

A

Macrophages

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11
Q

90% of iron is..

A

Recycled

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12
Q

15% of RBCs are list through..

A

Hemolysis

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13
Q

Decreased numbers of RBCs

A
Blood loss 
RBC destruction 
Decreased production (lack of needed elements, myelosuppression)
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14
Q

Hemoglobin is composed of

A

Heme (pigment), contains iron

Globin: protein

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15
Q

Hemoglobin determines..

A

Cell size and color

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16
Q

Hemoconcentration

A

If a person is dehydrated, it will look like they have more hemoglobin

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17
Q

Hematocrit

A

Measurement (%) space occupied by RBCs in plasma

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18
Q

Normal hematocrit values for men and women

A

Men 40-54%

Women 37-47%

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19
Q

Hematocrit is about ___ hemoglobin

A

3x

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20
Q

Reticulocyte count is only meaningful

A

In relation to total # or RBCs

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21
Q

Increased relic count

A

Over production of RBCs
Hemolysis
Blood loss

22
Q

Decreased retic count

A

Deficiency of BM production
Iron deficiency
Anemua
Infection

23
Q

RBC indices

A

MCV, MCH, MCHC

24
Q

MCH

A

Mean corpuscular Hgb

25
MCV
Mean corpuscular volume
26
MCHC
Mean corpuscular Hgb concentration
27
Function of platelets
Vascular integrity, clotting
28
Normal platelet count
150,000-400,000 / mm3
29
Platelets live
~7-10 days
30
>400,000 platelet count
Thrombocytosis
31
Thrombocytosis
Myeloproliferative disorders Splenectomy Advanced cancer Cirrhosis
32
<150,000 platelets
Thrombocytopenia
33
Thrombocytopenia
``` Idiopathic thrombocytopenia purpura Chemotherapy Anemias Infection Toxins ```
34
Clinical alert of platelets
<20,000
35
WBCs normal
5,000-10,000 / mm3
36
WBCs live..
12 hours in blood
37
Granulocytes
50-70% WBC count
38
Neutrophils
Primary defense against bacteria, stress
39
Eosinophils
Inflammatory and allergic reactions Parasitic infections Diurnal rhythm highest in am
40
Eosinophilia occurs in response to...
Worms Wheezes Weird diseases
41
Basophils
Contain histamine and heparin Migrate to tissue mast cells Mosquito bite
42
Stabs or bands
Immature granulocytes Increased in acute infections "shift to the left"
43
Agranulocytes
20-40% WBCs
44
Lymphocytes
20-40% | Indicator for viral infections and or chronic inflammation
45
B lymphocytes
Humoral immunity | produce antibodies
46
T lymphocytes
Cell mediated immunity
47
Lymphocytosis
Viral infections acute or chronic bacterial infections Leukemia
48
Decreased lymphocytes
Leukemia | Immune deficiency disorders
49
Monocytes, macrophages
2-8%
50
Monocytes, macrophages aid in...
``` Immunity against viral fungal protozoal mycobacterial infections And active in cell mediated immunity ```