Lab interpretation Flashcards
Blood is ___% body weight
6-8
Blood is __% plasma and __% formed elements
55
45
Women have __ L of blood and men have __ L
4.5-5.5
5-6
Plasma is __% water and __% proteins
92
7
Reticulocyte
Before erythrocyte, has a nucleus and when it loses it it becomes erythrocyte
RBC production is stimulated by..
Erythropoietin
Increased RBCs
Polycythemia
Decreased RBCs
Anemia
Life cycle of RBCs
120 days, 0.8% replaced daily
85% of RBCs are recycled by…
Macrophages
90% of iron is..
Recycled
15% of RBCs are list through..
Hemolysis
Decreased numbers of RBCs
Blood loss RBC destruction Decreased production (lack of needed elements, myelosuppression)
Hemoglobin is composed of
Heme (pigment), contains iron
Globin: protein
Hemoglobin determines..
Cell size and color
Hemoconcentration
If a person is dehydrated, it will look like they have more hemoglobin
Hematocrit
Measurement (%) space occupied by RBCs in plasma
Normal hematocrit values for men and women
Men 40-54%
Women 37-47%
Hematocrit is about ___ hemoglobin
3x
Reticulocyte count is only meaningful
In relation to total # or RBCs
Increased relic count
Over production of RBCs
Hemolysis
Blood loss
Decreased retic count
Deficiency of BM production
Iron deficiency
Anemua
Infection
RBC indices
MCV, MCH, MCHC
MCH
Mean corpuscular Hgb
MCV
Mean corpuscular volume
MCHC
Mean corpuscular Hgb concentration
Function of platelets
Vascular integrity, clotting
Normal platelet count
150,000-400,000 / mm3
Platelets live
~7-10 days
> 400,000 platelet count
Thrombocytosis
Thrombocytosis
Myeloproliferative disorders
Splenectomy
Advanced cancer
Cirrhosis
<150,000 platelets
Thrombocytopenia
Thrombocytopenia
Idiopathic thrombocytopenia purpura Chemotherapy Anemias Infection Toxins
Clinical alert of platelets
<20,000
WBCs normal
5,000-10,000 / mm3
WBCs live..
12 hours in blood
Granulocytes
50-70% WBC count
Neutrophils
Primary defense against bacteria, stress
Eosinophils
Inflammatory and allergic reactions
Parasitic infections
Diurnal rhythm highest in am
Eosinophilia occurs in response to…
Worms
Wheezes
Weird diseases
Basophils
Contain histamine and heparin
Migrate to tissue mast cells
Mosquito bite
Stabs or bands
Immature granulocytes
Increased in acute infections
“shift to the left”
Agranulocytes
20-40% WBCs
Lymphocytes
20-40%
Indicator for viral infections and or chronic inflammation
B lymphocytes
Humoral immunity
produce antibodies
T lymphocytes
Cell mediated immunity
Lymphocytosis
Viral infections
acute or chronic bacterial infections
Leukemia
Decreased lymphocytes
Leukemia
Immune deficiency disorders
Monocytes, macrophages
2-8%
Monocytes, macrophages aid in…
Immunity against viral fungal protozoal mycobacterial infections And active in cell mediated immunity