Lab Exam 2 (Lab Book) Flashcards
structural division of respiratory system
1) upper: nasal cavity, nose, pharynx, larynx
2) lower: trachea, bronchi, bronchioles
functional division of respiratory system
1) conducting: nasal cavity, pharynx, larynx, trachea, bronchi, terminal bronchioles
2) respiratory: respiratory bronchioles, alveolar ducts, alveoli
conducting portion features
- lined by respiratory mucosa
- function: filter, warm and moisten air
respiratory mucosa
1) pseudostratified ciliated (motile to sweep mucus and trapped contaminants towards pharynx for swallowing or expulsion) columnar epithelium with goblet cells (produce mucus) + stem cells
2) lamina propria: loose CT with BVs to warm air + mucous glands
respiratory portion features
- respiratory bronchiole branches from terminal bronchiole, then into alveolar ducts that lead into alveolar sac (made up of alveoli)
- function: where gas exchange takes place
epithelium in the larynx
- above vocal folds: stratified squamous nonkeratinized
- below: respiratory epithelium
serous membrane layers
1) visceral layer: around organ
2) parietal layer
- layers are continuous with each other
- layers produce serous fluid (lubricant) that fills serous cavity between them
tracheal rings
- trachea surrounded by 15-20 tracheal rings (anterior, c-shaped) and muscle (posterior, in front of esophagus)
annular ligaments
- join tracheal rings
- elastic cartilage allows for flexibility
carina of trachea
- bifurcation of trachea into right and left primary bronchi
branching of bronchial tree
1) trachea
2) primary bronchi: enter hilus of each lung, one per lung
3) lobar (secondary) bronchi: one per lung lobe
4) segmental (tertiary) bronchi: one per bronchopulmonary segment
5) bronchioles: each tertiary branches several times to form these
6) terminal bronchioles
trachea structure
- connects larynx to primary bronchi
- lined with respiratory mucosa
- cartilage rings anteriorly
- trachealis muscle (smooth) posteriorly: relaxes with SyNS stimulation for bronchodilation
layers of trachea epithelium
1) respiratory epithelium (mucosa)
2) lamina propria (mucosa)
3) seromucous glands in submucosa
4) perichondrium
5) hyaline cartilage ring
right/left lung lobes
- right = superior, middle and inferior
- left = superior and inferior
bronchopulmonary segments
- 9-10 in each lung
- each has tertiary bronchus
benefit of lung segmentation
- diseased segments can be removed while preserving function of others
bronchi histology
- respiratory mucosa with fewer goblet cells
- amount of cartilage decreases moving through bronchi (inhibit gas exchange)
- circular layer of smooth muscle appears in bronchi (can change size of tube, modulates SA)
- lots of lymphocytes
bronchiole histology
- epithelium becomes simple ciliated columnar/cuboidal, then simple cuboidal/low columnar (bronchiolar exocrine aka club cells)
- no mucosal glands or cartilage
- smaller, less circular lumen than bronchi
- more smooth muscle (prominent bundles lead to distinct shape)
- adjacent to blood vessels
- surrounded by alveoli
- lots of lymphocytes
respiratory portion branching
1) respiratory bronchioles: from terminal bronchioles, decreasing smooth muscle
2) alveolar ducts: no smooth muscle
3) alveolar sac: collections of alveoli
4) alveoli
pulmonary lobule
- branches of pulmonary arteries form capillary beds around alveoli for gas exchange
- pulmonary artery -> pulmonary arteriole -> pulmonary venules -> pulmonary vein -> heart
respiratory bronchiole histology
- lined with bronchiolar exocrine cells
- surrounded by few alveoli
- subdivide into alveolar ducts with simple squamous epithelium
- pulmonary arteries and veins visible
alveoli characteristics
- site of gas exchange, resembles a pouch (open on one side to alveolar duct/sac)
- between alveoli: interalveolar septa with fibroblasts, elastic (spongy) and reticular (maintain shape) fibers + pulmonary capillaries
- two types of cells (pneumocytes) and macrophages
type I alveolar cells
- numerous
- form simple squamous epithelium
type II alveolar cells
- rounded cells, vacuolated cytoplasm
- not as numerous
- secrete surface-active agent (surfactant) to decrease surface tension and maintain alveolar patency (sacs remain open)