Lab 5 - Endocrine

Question 1

Hypothalamus

Answer 1

• controls the anterior pituitary through the release of tropic hormones
  
  • secretion of anterior pituitary hormones is stimulated by tropic hormones from the hypothalamus

Question 2

Negative Feedback Loop of Thyroid Hormone Pathway

Answer 2

• hypothalamus –> anterior pituitary –> thyroid gland
• TRH –> TSH –> T4 and T3
• if TSH levels are low, the hypothalamus will increase the release of TRH

Question 3

Thyroid Hormone

Answer 3

hyperthyroidism: associated with increase in production of T3 and T4
- higher hormone secretion sees increase in BMR

Question 4

Rat Experiment

Question 5

Insulin

Answer 5

• released when high glucose levels
• gluconeogenesis forms glycogen from glucose
• alpha cells produce glucagon (catabolic)
• beta cells produce insulin (anabolic)

Question 6

Type 1 Diabetes

Answer 6

• no insulin produced due to beta cell destruction
• “juvenile” childhood onset
• large genetic component

Question 7

Type 2 Diabetes

Answer 7

• cells are resistant to insulin
• result in impaired insulin receptor function
• usually adult onset, although incident is increasing in young adults and children
• genetic component but major role in lifestyle factors