CH 7, Part 1-4 Flashcards
Central Nervous System (CNS)
Made up of brain and spinal cord
Peripheral Nervous System (PNS)
Nerves
Structural Classes of a Neuron
- inside of nerves are neurons
(1) Motor Neurons- “efferent neurons”
- send info in form of electrical impulses from CNS outwards, towards periphery of body (heart, skin, muscles, etc.)
(2) Sensory Neurons - “afferent neurons”
- send info from periphery of body back towards CNS
Motor Neurons
(1) Somatic
- conscious control over when neurons pass info from CNS to periphery
- all go to skeletal muscle fibers which allow body to move
(2) Autonomic
- goes to organs throughout body and generates electrical impulses on their own
- do NOT have conscious control over
(a) Sympathetic
- causes fight or flight response (prepare for physical activity)
- release norepinephrine -> heart rate and respiratory rate increase, digestion decreases
(b) Parasympathetic
- part of rest and digest nervous system
- activated during relaxation
- heart rate and respiratory rate decrease, digestion increases
Anatomy of a Neuron
DENDRITE
- thousands of extensions that come off of cell body
- receive info, send info to axon hillock
AXON
- one long projection
AXON HILLOCK
- beginning of an axon
- receives info from dendrites and decides if action potential will happen or not
AXON TERMINAL
- branches of an axon
AXON TERMINAL BUTTON
- filled with vesicles containing neurotransmitters
- pass info to another neuron’s dendrites
STRUCTURAL ORGANIZATION
- Nucleus: collection of neuronal cell bodies in CNS
- Nerve: bunch of axons bound together in PNS
- Ganglion: collection of cell bodies within a nerve
Myelin Sheath
- wrapping of fat (fatty acids) that exist around the axons
- elongated plasma membrane of cell wrapped around an axon of a neuron
- allows action potentials to propagate significantly faster
- most of myelinated neurons’ axons are wrapped
- Oligodendrocytes: creates myelin sheath around neurons in CNS
- can create multiple sections of myelin sheath around multiple different neurons
- Schwann cells: creates myelin sheath in PNS
- only creates one section of myelin sheath around one neuron
Resting Membrane Potential
- every cell in body is negatively charged
- interior of a neuron is -70 mV
- difference in voltage across the plasma membrane
(1) Chemical Driving Force
- diffusion gradient
- high –> low
(2) Electrical Driving Force
- inside of cell negatively charged so will pull ions with positive charge towards it
- fluid must be charged
- will pull ions with opposite (positive) charge towards it
- Equilibrium Potentials (Ek): When chemical and electrical driving forces are equal
- Cells are significantly more permeable to K+ than Na+
- the more permeable the membrane is to an ion, the closer mV will be to that ion’s Ex
Action Potentials
- electrical wave of changes in the voltage across a membrane
- occur in membranes of excitable cells in response to graded potentials that sum together to reach a threshold
- not decremental, so can be propagated long distances without a decrease in amplitude
Neuron Repolarization
- Neurons can generate around 2,000 action potentials in 1 second
- So must get regions of +30 mV back to -70 mV so that one can occur