LA Flashcards
WHAT DO YOU PALPATE WHEN DOING AN IDB
coronoid notch
ascending ramus
pterygomandibular raphe
HOW DO YOU ASPIRATE
push forward a tiny bit and let go
look for blood
WHY ASPIRATE
to avoid injecting LA into the BV
HOW LONG SHOULD YOU BE INJECTING IN AN IDB
30-45seconds
WHEN DOING AN IDB HOW MUCH OF THE CARTRIDGE SHOULD U DEPOSIT BEFORE RETRACTING
2/3 - last bit for lingual nerve - continuously injecting as retracting out the tissue
HOW LONG TIL FULLY ANAESTHETISED AFTER IDB
3-4 mins
HOW DO YOU DISPOSE OF THE NEEDLE
re-sheath - 1 click
secure - 2 clicks
remove the LA cartridge - blue bin
needle in orange bin
WHICH LA CANT BE USED IN PREGNANT WOMEN
prilocaine as it contains felypressin
WHAT DOES FELYPRESSIN DO TO PREGNANT WOMEN
induces labour
WHICH VASOCONSTRICTOR HAS CONSIDERATIONS WITH HEART PATIENTS AND WHY
adreneline as it can cause heart palpitations when acting on alpha receptors
IN WHAT SCENARIO WOULD YOU USE ARTICAINE OVER LIDOCAINE
when you are trying to anaesthetise a bigger area with less injections / avoiding a palatal as articaine is 4% compared to 2% lidocaine ( same vasoC)
WHY DOES FELYPRESSIN LA’S WASH OUT FASTER THAN ADRENLINE ONES
as adrenaline provides haemostatic control which means it doesn’t wash out as fast
WHAT CAN HAPPEN IF WE INJECT TOO STRAIGHT ON FOR AN IDB
hit parotid gland which contains facial nerve causing bells palsy
WHAT TO DO IF YOU GIVE THEM BELLS PALSY
don’t panic, pretty normal
send home with eyepatch so eye doesn’t dry up as cant close on own
HOW TO TELL THE DIFFERENCE BETWEEN A STROKE AND LA INDUCED PALSY
stroke = can still use forehead muscles
bells palsy = cant move anywhere on that side, all droopy
WHEN GIVING LA WHICH HAND IS USED FOR WHICH ACTION
dominant hand to inject
non dom to retract tissues
WHICH LA INJECTION WOULD HAVE THE PATIENT LYING THE FLATTEST
palatal
then buccal
then IDB
WHAT ARE THE MAIN LA PREPARATIONS
lidocaine 2% HCl = + 1:80000 adreneline
prilocaine 3% HCl + felypressin (0.03U/ml)
articaine 4% + 1:200000 adreneline
WHAT IS THE RESTING MEMBRANE POTENTIAL
-70mV
WHAT IS DEPOLARISATION OF AXON CAUSED BY
influx of Na+ ions through ion gated channels into the cell
WHAT IS REPOLARISATION CAUSED BY
efflux of K+ ions through ion gated channels
WHY IS THERE A REFRACTORY PERIOD IN ACTION POTENTIALS
as the Na+ ion channels are inactivated from previous AP
so AP cant propagate
IS THE ICF NEGATIVE OR POSITIVE
negative - more K+
WHAT FEATURES OF AN AXON MAKE IT HAVE QUICKER CONDUCTION SPEED
larger and myelinated
WHAT IS SALTATORY CONDUCTION
the AP passes along myelinated axons by skipping from one node of Ranvier to the next - fast
HOW DOES LA WORK PHYSIOLOGICALLY
blocks the Na+ voltage gated ion channels so depolarisation is blocked
WHICH AXON TYPES FUNCTION IS MOST LIKELY TO STILL BE FELT AFTER LA AND WHY
Aa as its the biggest axon with the most Na channels to be blocked so the least susceptible
COMPOSITION OF LA
the LA
- aromatic region
- ester or amide bond
- hydrophilic region
reducing agent
preservatives / fungicides
vasoC
WHICH COMPONENT OF LA IS HYDROPHOBIC AND WHY DO WE NEED IT
the aromatic region
to pass through the membrane
WHY DO WE NEED A HYDROPHILIC REGION OF LA
to be soluble in water to be in an injection solution
WHY DO WE NEED A HYDROPHILIC REGION OF LA
to be soluble in water to be in an injection solution
WHEN IS LA IN ACTIVE FORM
when it is ionised (has H)
after inside the cell
WHEN IS LA IN INACTIVE FORM
when its unionised (H removed)
when passing membrane
HOW IS LA WRITTEN CHEMICALLY
B.HCl
WHAT IS THE REDUCING AGENT IN LA
sodium metabisulphide
WHICH LA ARE ESTER BOND
benzocaine
cocaine
procaine
WHICH LA ARE ESTER BOND
benzocaine
cocaine
WHICH LA ARE AMIDE BOND
lidocaine
prilocaine
articaine
WHY DO LA SOLUTIONS NEED A VASOCONSTRICTOR
as LA work as vasodilators which washes the LA out faster
TYPES OF VASOCONSTRICTOR
adrenline
felypressin
WHAT IS THE EFFECT WHEN ADRENLINE WORKS ON ALPHA ADRENORECEPTORS
vasoconstriction
WHAT IS THE EFFECT WHEN ADRENELINE WORKS ON B1 ADRENORECEPTORS
heart palpitations when given systemically
WHICH RECEPTORS DOES FELYPRESSIN WORK ON
ADH - anti diuretic hormone - receptors
HOW IS LA INACTIVATED FROM TISSUES
washed out by blood supply
esterases
liver amidases