L8: viral infections extras (types of HPV and also, rubella) Flashcards

1
Q

verruca vulgaris is hpv what?

A

hpv 2 and 4

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2
Q

verruca vulgaris often affects what type of ppl

A

children

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3
Q

clinical presentation of verruca vulgaris

  • white _____/ nodule (5mm)
  • _____ projections or rough ______ surface
  • painless, _________/sessile
  • _____/ keratin horn
A
  • white papule/ nodule (5mm)
  • papillary projections or rough pebbly surface
  • painless, pedunculated/sessile
  • cutaneous/ keratin horn
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4
Q

what is the name of a common wart

A

verruca vulgaris

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5
Q

location of verruca vulgaris

A
  • vermillion border, labial mucosa
  • anterior tongue
  • skin of hands
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6
Q

clincial presentation of verruca vulgaris

  • white papule/ _____ (how many mm?)
  • _______ or rough pebbly surface
  • painful or not?
  • pedunculated/_____
  • cutaneous/ _____
A
  • white papule/ nodule (5mm)
  • papillary projections or rough pebbly surface
  • painless
  • pedunculated/sessile
  • cutaneous/ keratin horn
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7
Q

squamous papilloma is associated with what strains of hpv

A

6 and 11

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8
Q

squamous papilloma clinical presentation

  • mainly in what type of ppl?
  • solitary or multiple?
  • _____ nodule (0.5-3mm)
  • _____ like surface projections, blunted/pointed
  • ______ or wart like appearance
  • painless or painful?
  • pedunculated, soft
  • what colour?
A
  • mainly in adults (30-50 yo)
  • solitary
  • exophytic nodule (0.5-3mm)
  • finger like surface projections, blunted/pointed
  • cauliflower or wart like appearance
  • painless, pedunculated, soft
  • white/ red/ normal in colour (depend on amunt of surface keratinisation)
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9
Q

where are lesions of squamous papilloma found?

A

anywhere in mouth
is the most common soft tissue mass on soft palate

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10
Q

clinical presentation of condyloma acuminatum

  • affects what type of ppl? what type of transmission?
  • _________ , ____mass (1cm)
  • short, ______ surface projections
  • painless or painful?
  • mobile or sessile (immobile)?
  • what colour?
  • may cluster together
A
  • teenagers and young adults (sexually transmitted)
  • well demarcated, exophytic mass (1cm)
  • short, blunted surface projections
  • painless
  • sessile
  • pink
  • may cluster together
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11
Q

which hpv strain is associated with condyloma acuminatum?

A

hpv 6 and 11

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12
Q

where is condyloma acuminatum found in the oral cavity?

A
  • labial mucosa
  • soft palate
  • lingual frenum
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13
Q

rubeola aka measles is under what virus family?

A

paramyxovirus

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14
Q

incubation time of rubeola

A

10-12 days

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15
Q

when is rubeola infective?

A

2 days before symptoms to 4 days after appearance of rash

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16
Q

how does rubeola spread?

A

airborne

17
Q

clinical features of rubeola:

  • __________ – peyer’s patches, tonsils, adenoids, lymph nodes
  • _____ due to giant cell infiltration
A
  • lymphoid hyperplasia – peyer’s patches, tonsils, adenoids, lymph nodes
  • vasculitis due to giant cell infiltration
18
Q

clinical features of rubeola
- lymphoid hyperplasia - ________ patches, tonsils, adenoids, lymph nodes
- vasculitis due to ________

A
  • lymphoid hyperplasia – peyer’s patches, tonsils, adenoids, lymph nodes
  • vasculitis due to giant cell infiltration
19
Q

How many stages in measles?

A

3 stages lasting 3 days each

20
Q

1st stage of measles have what characteristics? (3 Cs)

A
  • coryza (inflammation of mucous membrane in nose_
  • cough
    -conjunctivitis
  • also got Koplik’s spots
21
Q

what are Kopliks spots

  • ____ white macules within _____ mucosa
  • foci of _________
  • ____ on red bg appearance
  • can involve oral, conjunctiva, and/or vaginal mucosa
A
  • bluish white macules within erythematous mucosa
  • foci of epithelial necrosis
  • grains of salt on red bg appearance
  • can involve oral, conjunctiva, and/or vaginal mucosa
22
Q

what happens in 2nd stage of measles?

-______ fade away
- ______, morbilliform ____ develops
- _____ is the first to be involved
- gradual downward spread to trunk and extremities
- ______ on pressure
- abdominal pain from ______ is possible

A
  • Kopliks spots fade away
  • maculopapular, morbilliform rash develops
  • face is the first to be involved
  • gradual downward spread to trunk and extremities
  • blanch on pressure
  • abdominal pain from lymphadenopathy is possible
23
Q

what happens in 3rd stage of measles?

  • ____ ends
  • ____ starts to fade in downward progression
  • replaced by brown _______ with ______ of skin
A
  • fever ends
  • rash starts to fade in downward progression
  • replaced by brown hyperpigmentation with desquamation of skin
24
Q

in young children, measles can affect what process?

A

odontogenesis

25
Q

in immunocompromised px, if they get measles they can have what complications?

A

-candidiasis
- NUG or stomatitis

26
Q

common complications of measles?

A
  • otitis media (ear inflammation)
  • pneumonia
  • persistent bronchitis
  • diarrhea
27
Q

rare delayed complication of measles?

A

subacute sclerosing panencephalitis

  • up to as late as 11 years
  • will see cns changes like personality change, seizure, coma and death
28
Q

at what age is measles vaccination given?

A

two doses:

first one at 12-15 months
booster at 4-6 yo

29
Q

what kind of supportive care should be given to px with measles?

A
  • antipyretics but avoid aspirin for risk of reyes syndrome
  • antirivrals in immunocompromised px like Ribavarin, interferon and immunoglobulin
30
Q

rubella not the same as rubeola
rubella caused by what kind of virus?

A

togavirus

31
Q

rubella spread by what

A

airborne

32
Q

incubation time for rubella

A

14-21 days

33
Q

infective period for rubella

A

7 days before rash to 5 days after devleopment of rash

34
Q

classic triad of congenital rubella syndrome

A
  • deafness
  • heart disease
  • cataract
35
Q

for rubella, rash resolves by when

A

by day 3

36
Q

clinical features of rubella

_____ sign:
- small, discrete ______ papules on the soft +/- hard palate
- occurs _____ with the ___ but last no longer than ______ hours

palatal _______ maybe present

A

forcheimer’s sign:
- small, discrete dark red papules on the soft +/- hard palate
- occurs simultaneously with the rash but last no longer than 12 -14 hours

palatal petechiae maybe present

37
Q

for rubella, passive immunity can be rendered by administering _____

  • given when?
  • given to whom>
A

adminstering human rubella immunoglobulin

  • given in the first few days to decrease severity
  • only given to pregnant women who decline abortion
38
Q

epidemic parotitis is known as what and is caused by what virus

A

mumps, paramyxovirus family