L8: viral infections extras (types of HPV and also, rubella) Flashcards
verruca vulgaris is hpv what?
hpv 2 and 4
verruca vulgaris often affects what type of ppl
children
clinical presentation of verruca vulgaris
- white _____/ nodule (5mm)
- _____ projections or rough ______ surface
- painless, _________/sessile
- _____/ keratin horn
- white papule/ nodule (5mm)
- papillary projections or rough pebbly surface
- painless, pedunculated/sessile
- cutaneous/ keratin horn
what is the name of a common wart
verruca vulgaris
location of verruca vulgaris
- vermillion border, labial mucosa
- anterior tongue
- skin of hands
clincial presentation of verruca vulgaris
- white papule/ _____ (how many mm?)
- _______ or rough pebbly surface
- painful or not?
- pedunculated/_____
- cutaneous/ _____
- white papule/ nodule (5mm)
- papillary projections or rough pebbly surface
- painless
- pedunculated/sessile
- cutaneous/ keratin horn
squamous papilloma is associated with what strains of hpv
6 and 11
squamous papilloma clinical presentation
- mainly in what type of ppl?
- solitary or multiple?
- _____ nodule (0.5-3mm)
- _____ like surface projections, blunted/pointed
- ______ or wart like appearance
- painless or painful?
- pedunculated, soft
- what colour?
- mainly in adults (30-50 yo)
- solitary
- exophytic nodule (0.5-3mm)
- finger like surface projections, blunted/pointed
- cauliflower or wart like appearance
- painless, pedunculated, soft
- white/ red/ normal in colour (depend on amunt of surface keratinisation)
where are lesions of squamous papilloma found?
anywhere in mouth
is the most common soft tissue mass on soft palate
clinical presentation of condyloma acuminatum
- affects what type of ppl? what type of transmission?
- _________ , ____mass (1cm)
- short, ______ surface projections
- painless or painful?
- mobile or sessile (immobile)?
- what colour?
- may cluster together
- teenagers and young adults (sexually transmitted)
- well demarcated, exophytic mass (1cm)
- short, blunted surface projections
- painless
- sessile
- pink
- may cluster together
which hpv strain is associated with condyloma acuminatum?
hpv 6 and 11
where is condyloma acuminatum found in the oral cavity?
- labial mucosa
- soft palate
- lingual frenum
rubeola aka measles is under what virus family?
paramyxovirus
incubation time of rubeola
10-12 days
when is rubeola infective?
2 days before symptoms to 4 days after appearance of rash
how does rubeola spread?
airborne
clinical features of rubeola:
- __________ – peyer’s patches, tonsils, adenoids, lymph nodes
- _____ due to giant cell infiltration
- lymphoid hyperplasia – peyer’s patches, tonsils, adenoids, lymph nodes
- vasculitis due to giant cell infiltration
clinical features of rubeola
- lymphoid hyperplasia - ________ patches, tonsils, adenoids, lymph nodes
- vasculitis due to ________
- lymphoid hyperplasia – peyer’s patches, tonsils, adenoids, lymph nodes
- vasculitis due to giant cell infiltration
How many stages in measles?
3 stages lasting 3 days each
1st stage of measles have what characteristics? (3 Cs)
- coryza (inflammation of mucous membrane in nose_
- cough
-conjunctivitis - also got Koplik’s spots
what are Kopliks spots
- ____ white macules within _____ mucosa
- foci of _________
- ____ on red bg appearance
- can involve oral, conjunctiva, and/or vaginal mucosa
- bluish white macules within erythematous mucosa
- foci of epithelial necrosis
- grains of salt on red bg appearance
- can involve oral, conjunctiva, and/or vaginal mucosa
what happens in 2nd stage of measles?
-______ fade away
- ______, morbilliform ____ develops
- _____ is the first to be involved
- gradual downward spread to trunk and extremities
- ______ on pressure
- abdominal pain from ______ is possible
- Kopliks spots fade away
- maculopapular, morbilliform rash develops
- face is the first to be involved
- gradual downward spread to trunk and extremities
- blanch on pressure
- abdominal pain from lymphadenopathy is possible
what happens in 3rd stage of measles?
- ____ ends
- ____ starts to fade in downward progression
- replaced by brown _______ with ______ of skin
- fever ends
- rash starts to fade in downward progression
- replaced by brown hyperpigmentation with desquamation of skin
in young children, measles can affect what process?
odontogenesis
in immunocompromised px, if they get measles they can have what complications?
-candidiasis
- NUG or stomatitis
common complications of measles?
- otitis media (ear inflammation)
- pneumonia
- persistent bronchitis
- diarrhea
rare delayed complication of measles?
subacute sclerosing panencephalitis
- up to as late as 11 years
- will see cns changes like personality change, seizure, coma and death
at what age is measles vaccination given?
two doses:
first one at 12-15 months
booster at 4-6 yo
what kind of supportive care should be given to px with measles?
- antipyretics but avoid aspirin for risk of reyes syndrome
- antirivrals in immunocompromised px like Ribavarin, interferon and immunoglobulin
rubella not the same as rubeola
rubella caused by what kind of virus?
togavirus
rubella spread by what
airborne
incubation time for rubella
14-21 days
infective period for rubella
7 days before rash to 5 days after devleopment of rash
classic triad of congenital rubella syndrome
- deafness
- heart disease
- cataract
for rubella, rash resolves by when
by day 3
clinical features of rubella
_____ sign:
- small, discrete ______ papules on the soft +/- hard palate
- occurs _____ with the ___ but last no longer than ______ hours
palatal _______ maybe present
forcheimer’s sign:
- small, discrete dark red papules on the soft +/- hard palate
- occurs simultaneously with the rash but last no longer than 12 -14 hours
palatal petechiae maybe present
for rubella, passive immunity can be rendered by administering _____
- given when?
- given to whom>
adminstering human rubella immunoglobulin
- given in the first few days to decrease severity
- only given to pregnant women who decline abortion
epidemic parotitis is known as what and is caused by what virus
mumps, paramyxovirus family
