L8&9

Question 1

caused mainly by infection with one of the five hepatitis viruses, which use the liver as their primary site of replication.

Answer 1

Viral hepatitis

Question 2

transmit via the faecal–oral route.

Answer 2

HAV and HEV

Question 3

transmitted in blood and other body fluids

Answer 3

HBV and HCV

Question 4

can only infect people already infected with hepatitis B.

Answer 4

HDV

Question 5

is a small, enveloped, positive single-stranded RNA virus.

Answer 5

HCV

Question 6

family of HCV

Answer 6

Flaviviridae

Question 7

particles of …… are spherical and heterogenousin size, typically ranging 40-80 nm in diameter.

Answer 7

HCV

Question 8

are sensitive and are used for initial diagnostic of hepatitis C, for screening of blood and organ donations and for confirming SVR after treatment completion

Answer 8

Qualitative PCR tests

Question 9

can detect and quantify the HCV RNA.

Answer 9

Quantitative reverse transcriptase (RT) real-time PCR