L10 Flashcards
are spherical and have spike protein projections on their surface resulting in a crown-like morphology, leading to their nomenclature.
Coronaviruses
are enveloped by a lipid bilayer. non-segmented positive-sense RNA viruses
Coronaviruses
approximately 30Kb in length with a 5′-cap structure and 3′-poly-A tail.
SARS-CoV-2
encode 16 non-structural proteins
ORF1b genes, in sars-cov2
is a drug approved for the treatment of influenza and other respiratory viral infections.
Umifenovir
is approved in Japan for the treatment of pancreatitis.
Camostat mesylate
interfere with the entry of SARS-CoV-2. used in the prevention and treatment of malaria and autoimmune diseases
Chloroquine and hydroxychloroquine
originally developed to treat hepatitis C
Remdesivir
- developed to treat influenza virus.
- reduced the disease signs on chest imaging
Favilavir