L77: Autonomic nervous system Flashcards
Explain the flow chart of the nervous system?
- NS
- CNS and PNS
- CNS=BRAIN AND SPINALCORD, BUT PNS= sensory s, autonomic NS somatic NS
- Autonomic NS= SYMTHETIC NS AND PARASYMPATHETIC NS
what are the 4 main roles of the autonomic nervous system?
– Control of cardiac function – Contraction and relaxation of smooth muscle
– Control of exocrine and some endocrine glands
– Regulation of energy metabolism
how many neurons are there for the autonomic nervous system pathway?
2
what is the nervous pathway for the autonomic nervous system?
The pre-ganglionic neuron has its cell body in the CNS and synapses in the autonomic ganglion; the postganglionic neuron has its cell body in the autonomic ganglion and synapses with the effector organ
In the pre-sympathetic NS where does the pre-ganglionic sympathetic neurons leave in the sympathetic NS?
the thoracic and lumbar regions of the spinal cord. synapse at ganglia close to the spinal cord
what neurotransmitter do post-ganglionic sympathetic neurones release in the sympathetic NS?
noradrenaline
In the sympathetic NS what are the lengths of the ganglion neurons?
long post-ganglion short pre ganglion neurons
In the pre-sympathetic NS where does the pre-ganglionic parasympathetic neurons leave in the parasympathetic NS?
leaves from the brainstem and the sacral region of the spinal cord. then synapse at ganglia close to the effectors organ
In the parasympathetic NS what are the lengths of the ganglion neurons?
-long pre-ganglionic neuron and short post ganglionic neurons
what neurotransmitter do post-ganglionic parasympathetic neurones release in the parasympathetic NS?
acetylcholine
what receptors do acetylcholine act on in the autonomic NS?
- nicotinic they are ligand gated ion channels
- Muscarinic they are G protein-coupled receptors
where is acetylcholine released from?
released from both sympathetic and parasympathetic preganglionic neurons as well as synapses with the adrenal medulla and parasympathetic post-ganglionic neuron and acts as a muscarinic receptor at the synapse.
what are the different types of muscarinic receptors?
M1, M2, M3, M4 and M5
where is noradrenaline released from?
the post-ganglionic neuron of the sympathetic NS?
where does noradrenaline act on?
adrenoceptors at the synapse with the target organ this will stimulate a response