L77: Autonomic nervous system Flashcards

1
Q

Explain the flow chart of the nervous system?

A
  • NS
  • CNS and PNS
  • CNS=BRAIN AND SPINALCORD, BUT PNS= sensory s, autonomic NS somatic NS
  • Autonomic NS= SYMTHETIC NS AND PARASYMPATHETIC NS
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2
Q

what are the 4 main roles of the autonomic nervous system?

A

– Control of cardiac function – Contraction and relaxation of smooth muscle
– Control of exocrine and some endocrine glands
– Regulation of energy metabolism

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3
Q

how many neurons are there for the autonomic nervous system pathway?

A

2

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4
Q

what is the nervous pathway for the autonomic nervous system?

A

The pre-ganglionic neuron has its cell body in the CNS and synapses in the autonomic ganglion; the postganglionic neuron has its cell body in the autonomic ganglion and synapses with the effector organ

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5
Q

In the pre-sympathetic NS where does the pre-ganglionic sympathetic neurons leave in the sympathetic NS?

A

the thoracic and lumbar regions of the spinal cord. synapse at ganglia close to the spinal cord

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6
Q

what neurotransmitter do post-ganglionic sympathetic neurones release in the sympathetic NS?

A

noradrenaline

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7
Q

In the sympathetic NS what are the lengths of the ganglion neurons?

A

long post-ganglion short pre ganglion neurons

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8
Q

In the pre-sympathetic NS where does the pre-ganglionic parasympathetic neurons leave in the parasympathetic NS?

A

leaves from the brainstem and the sacral region of the spinal cord. then synapse at ganglia close to the effectors organ

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9
Q

In the parasympathetic NS what are the lengths of the ganglion neurons?

A

-long pre-ganglionic neuron and short post ganglionic neurons

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10
Q

what neurotransmitter do post-ganglionic parasympathetic neurones release in the parasympathetic NS?

A

acetylcholine

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11
Q

what receptors do acetylcholine act on in the autonomic NS?

A
  • nicotinic they are ligand gated ion channels

- Muscarinic they are G protein-coupled receptors

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12
Q

where is acetylcholine released from?

A

released from both sympathetic and parasympathetic preganglionic neurons as well as synapses with the adrenal medulla and parasympathetic post-ganglionic neuron and acts as a muscarinic receptor at the synapse.

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13
Q

what are the different types of muscarinic receptors?

A

M1, M2, M3, M4 and M5

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14
Q

where is noradrenaline released from?

A

the post-ganglionic neuron of the sympathetic NS?

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15
Q

where does noradrenaline act on?

A

adrenoceptors at the synapse with the target organ this will stimulate a response

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16
Q

how many sub-units of adrenoceptors are there?

A

2
– α-adrenoceptors
– β-adrenoceptors