L7 - Protein Structure and Function I

Question 1

Secondary Structure

Answer 1

Folding of parts of the primary structure

Question 2

2 Structures in the Secondary structure

Answer 2

Alpha Helices
Beta Sheets

Question 3

How many Amino Acids make Alpha helices

Answer 3

5 - 40
3.6 per turn

Question 4

Vertical distance and Turn length of Alpha Helices

Answer 4

0.15nm vertical
0.54nm turn length

Question 5

Where do side chains project in Alpha Helices

Answer 5

Project out of the helix

Question 6

Beta strands

Answer 6

Non-contiguous regions either running in the same or opposite directions (parallel or antiparallel)

Question 7

Parallel Beta sheets

Answer 7

Hydrogen bonds evenly spaced
Strands almost fully extended

Question 8

Antiparallel Beta sheets

Answer 8

Narrowly spaced hydrogen bond pair separated by a larger gap
Strands almost fully extended

Question 9

Pleated sheet structure

Answer 9

Alpha carbons lie successively above and below the plan of the sheet

Question 10

Loop regions

Answer 10

Link Alpha helices and B sheets
Random coils

Question 11

Hairpin Loops

Answer 11

Short loops that connect antiparallel Beta strands
Proline and Glycine often found

Question 12

Beta - Alpha - Beta motif

Answer 12

Parallel strands are connected by an Alpha Helix