L7 Flashcards
HOW many species OF Staphylococcus ?
- Staphylococcus aureus.
- Staphylococcus epidermidis.
- Staphylococcus saprophyticus
Staphylococcus aureus
Gram ?
shapr?
arrange?
Catalase?
Gram-positive
cocci
arranged in ‘grape-like’ clusters.
Catalase positive
t or f
Staphylococcus aureus
Aerobic and facultatively anaerobic?
T
Coagulase and DNase positive in?
Staphylococcus aureus
Nasal carriage occurs in 30–50% of healthy adults
Staphylococcus aureus
it is Worldwide, all the seasons, all ages what bacteria?
Worldwide, all the seasons, all ages
what is the function of Protein A in Staphylococcus aureus?
inhibit phagocytosis
what is the function of Teichoic acid in Staphylococcus aureus?
mediated adherence to mucosal surface
name the enzymes of Staphylococcus aureus?
1- Coagulase = resistant to phagocytosis.
2- Catalase = degrade H₂O₂, limit phagocytic ability to kill bacteria
name the toxins of Staphylococcus aureus?
1- Super antigen
2- Heamolysin
are microbial peptides that can activate a large fraction of T cells.
Superantigens
The most common infection of Staphylococcus aureus?
Folliculitis
infection also involves hair follicle & the sebaceous gland, localized collection of pus
A furuncle (boil)
cluster of furuncles
Carbuncles
Common among children ( Honey crust )
Impetigo ( Pyoderma )
Infection of the skin folds of the nails
Paronychia
not (Tinea uniguium & onychomycosis)
In children follows a toxemia with infection of umbilical
stump or eyes and *Exfoliative toxin produced.
Scalded Skin Syndrome (SSS)
Resistance due to production of an additional Penicillin-binding protein, which is encoded by
mecA gene
Treatment of Staphylococcus aureus
flucloxacillin as first-line treatment
Treatment of MRSA
glycopeptides antibiotics as vancomycin
Treatment of VRSA
linezolid and daptomycin
S. epidermidis
foreign devices & biofilm protect it from antibiotics
and host defenses
S. saprophyticus
urinary tract infections in sexually active
young women.
Novobiocin resistant
S. saprophyticus
novobiocin sensitive
S. epidermidis