L6 Urine Flashcards
Body fluid distribution
Intracellular fluid 65%
Extracellular fluid 35%
Structure of urinary system
Kidney
Ureter
Urinary bladder
Urethra
Major structure of kidney
Renal cortex (outer)
Renal medulla ( middle)
Renal pyramid (triangle)
Major / minor calyx
Two type of nephron
Cortical nephron
to filtrate and excrete
Juxtamedullary nephron
Regulate concentration of urine & water balance
Ureter
Valve are open when bladder is relaxed
Urinary bladder
Max 700mL
Middle muscle layer controlled by autonomic nerve fibre
Urethra
Internal vs external
Twi muscle (upstream / downstream muscle) control the internal urethra orifice
Urination process
- Receptor send the signal to spinal cord
- Contraction of detrusor muscle + relaxation of internal urethral sphincter
- Cerebral cortex know the urge to urine
- Relax external urethral sphincter to urine
Urination process
- Receptor send the signal to spinal cord
- Contraction of detrusor muscle + relaxation of internal urethral sphincter
- Cerebral cortex know the urge to urine
- Relax external urethral sphincter to urine
Renal blood supply
- Afferent arteriole
- Glomerulus
- Efferent arteriole
- Peritubular capillary
- Renal vein
- Inferior vena cava
Rough urine production steps
- Glomerulus filtration
- Tubular reabsorption
- Tubular secretion
- Urine concentration
Glomerulus filtration rate affected by
Osmotic pressure
Hydrostatic of blood
Hydrostatic of glomerulus itself
Tubular reabsorption
Movement of substance e.g. water return to blood
Reduce amount of filtrate
Tubular secretion
More waste product are secreted from the blood
(Creatine, hydrogen, potassium, drugs)
Urine concentration (2 steps)
Reabsorb water in proximal tube
Step 1 juxamedullary nephron
Deeper the loop, higher the osmotic pressure
Step2
Higher osmotic pressure, more water drawn away from blood