L6 Pulmonary Flashcards
Weight of lungs
Which is heavier
200-250g
Right is heavier
Lung blood supply
Pulmonary
Bronchial
Types of alveoli
Type I: flat (95%)
Type II:Cuboidal, produce surfactant
Dyspnea
shortness of breath
Atelectasis
collapse or loss of lung volume
Transudate vs exudate
Trans: low protein, increased venous pressure
Exudate: high protein, from vascular damage/permeability
Causes of pulmonary edema (3)
Increased intravascular pressure
Hypoproteinemia
Vascular damage
Chronic obstructive pulmonary disease
Diseases that cause it (4)
Emphysema
Chronic bronchitis
Bronchiectasis
Asthma
Emphysema
Pathogensis: imbalance between
protease and anti-protease enzymes
Centriacinar vs panacinar Emphysema
Portion of lobule
Lobes
Associated with
Centri: -Central portion of lobule -Upper lobes -associated with smoking Pana: -Entire respiratory lobule -Lower lobes -alpha-1-AT deficiency
Chronic bronchitis defintion
cough with sputum for at least
3 consecutive months for 2 consecutive years
Bronchiectasis
Chronic infection w/ permanent airway dilation
Asthma pathology
What happens to certain cells
Immune system cells and chemicals
Mucus gland hypertropy/hyperplasia
Eosinophils
Type 2 helper T cells
IgE on mast cells, release histamin and leukotriense
Emphysema
permanent enlargement of distal small air spaces due to destruction of alveolar septal walls
Atopic vs nonatopic
Atopic: allergic, extrinsic: Type I hypersensitivity (IgE)
-environmental antigen
-family history
Non-atopic: intrinsic: viruses, air pollutants