L4: Bladder Cancer Flashcards
Incidence of Bladder Cancer
10 Per 100K
Incidence of Bladder Cancer
- Age
Incidence of Bladder Cancer
- Sex
Male: Female → 3:1
Incidence of Bladder Cancer
- Race
White race more than blacks.
Incidence of Bladder Cancer
- Occupation
- In Egypt: Farmers & Aniline workers.
- Abroad: Aniline workers.
RF for Bladder Cancer
RF for Bladder Cancer
- Most Evident
Smoking
RF for Bladder Cancer
- Chronic Irritation
- Chronic cystitis & bladder stone: Increase risk of SCC.
- Chronic urinary tract infection (UTI).
- Indwelling catheter: Increase Irritation + UTI.
RF for Bladder Cancer
- Biharziasis
Schistosoma haematobium + UTI.
RF for Bladder Cancer
- Radiation Exposure
…
Pathological Types of Bladder Cancer
Pathological Types of Bladder Cancer
- 1ry
Pathological Types of Bladder Cancer
- 2ry
Metastasis from Melanoma, Colon, Prostate, Lung, Breast.
Gross Picture of Bladder Cancer
Sites of Bladder Cancer
Staging of Bladder Cancer
Staging of Bladder Cancer
- T
Staging of Bladder Cancer
- N
Staging of Bladder Cancer
- M
Pre-Cancerous Lesion in bladder Cancer
Pre-Cancerous Lesion in SCC
- Squamous metaplasia
- Leukoplakia
Pre-Cancerous Lesion in Adenocarcinoma
Cystitis glandularis
Pre-Cancerous Lesion in TCC
Dysplasia (Atypia)
Pre-Cancerous Lesion in CIS
Dysplasia (Atypia)
CP of Bladder Cancer
Complications of Bladder Cancer
Investigations for Bladder Cancer
Investigations for Bladder Cancer
- Lab
Investigations for Bladder Cancer
- Rad
Rad Investigations for Bladder Cancer
Rad Investigations for Bladder Cancer
- KUB
Detect associated stones or eatening of calcification of the bladder.
Rad Investigations for Bladder Cancer
- US
Pelvic u/s in full bladder can detect masses.
Rad Investigations for Bladder Cancer
- IVP
Rad Investigations for Bladder Cancer
- CT
Rad Investigations for Bladder Cancer
- Pelvic MRI
…
Rad Investigations for Bladder Cancer
- Other Rads
Investigations for Bladder Cancer
- Cystoscopy & Biopsy
“Diagnostic”
- EUA: Examination under anesthesia
TTT of Bladder Cancer
Muscle Invasive Or Not
TTT of Bladder Cancer
- Depends on
1) Tumor stage
2) Tumor cell type
3) General condition of the patient
4) Patient compliance
5) Treatment facilities
TTT of Bladder Cancer
- Non-Muscle Invasive Tumours
TTT of Bladder Cancer
- Muscle Invasive Tumours
TTT of Bladder Cancer
- In Advanced (CT48) And/or Metastatic Disease
Def of Urinary Diversion
Storage of urine in a reservoir other than the bladder or passage of urine in a pathway other than normal urethra
Methods of Urinary Diversion
Complications of Diversions
Early & Late
Complications of Diversions
- Early Complications
Late Complications of Diversions
- Non-Metabolic
Metabolic Late Complications of Diversions