L2: NTDs Flashcards
1
Q
A
2
Q
Types of Neural Tube Defects
A
- Spina Bifida Occulta
- Tethered Cord
- Meningocele
- Myelomeningocele
3
Q
Incidence of Spina Bifida Occulta
A
Very mild but Common
4
Q
Spinal Cord Affection in Spina Bifida Occulta
A
Very rarely causes disability
5
Q
How to detect Spina Bifida Occulta?
A
- x-ray
- investigating a back injury.
6
Q
Incidence of Myelomeningocele
A
Most serious and common
7
Q
Spinal Cord Affection in Myelomeningocele
A
- The spinal cord is damaged or not properly developed resulting in motor and sensory deficit.
8
Q
CP of Myelomeningocele
A
- The cyst not only contains meninges and CSF but also the nerves and spinal cord.
- Majority have bowel and bladder problems
9
Q
Dx of NTDs
A
- MSAFP
- US
- Amniocentesis
10
Q
Senseitivity of AFP in detection of NTDs
A
91% sensitivity in spina bifida
11
Q
AFP in detection of NTDs
- Normal
A
12
Q
AFP in detection of NTDs
- What is Diagnostic Level?
A
High maternal serum AFP > 2 multiples of median for appropriate week of gestation.
13
Q
US in detection of NTDs
A
14
Q
US in detection of NTDs
- Advantages
A
- Diffrentiate NTD fron non-neurological causes of elevated AFP e.g. omphalocele
15
Q
Amniocentesis in detection of NTDs
A