L2: NTDs Flashcards
Types of Neural Tube Defects
- Spina Bifida Occulta
- Tethered Cord
- Meningocele
- Myelomeningocele
Incidence of Spina Bifida Occulta
Very mild but Common
Spinal Cord Affection in Spina Bifida Occulta
Very rarely causes disability
How to detect Spina Bifida Occulta?
- x-ray
- investigating a back injury.
Incidence of Myelomeningocele
Most serious and common
Spinal Cord Affection in Myelomeningocele
- The spinal cord is damaged or not properly developed resulting in motor and sensory deficit.
CP of Myelomeningocele
- The cyst not only contains meninges and CSF but also the nerves and spinal cord.
- Majority have bowel and bladder problems
Dx of NTDs
- MSAFP
- US
- Amniocentesis
Senseitivity of AFP in detection of NTDs
91% sensitivity in spina bifida
AFP in detection of NTDs
- Normal
AFP in detection of NTDs
- What is Diagnostic Level?
High maternal serum AFP > 2 multiples of median for appropriate week of gestation.
US in detection of NTDs
US in detection of NTDs
- Advantages
- Diffrentiate NTD fron non-neurological causes of elevated AFP e.g. omphalocele
Amniocentesis in detection of NTDs
Amniocentesis in detection of NTDs
- Uses
- Show elevated AFP between 12-15 week earlier than serum AFP
Amniocentesis in detection of NTDs
- Disadvantages
Carries 6% risk of abortion and fetal loss
Amniocentesis in detection of NTDs
- Indications
- Pregnancies subsequent to NTD
- Elevated AFP with Normal US
Factors associated with Increased Risk of NTDs
The only most significant risk factor associated with NTDs is
Folic Acid
Prophylaxis against NTDs
Nursing Care in NTDs
TTT aspects of NTDs
- Nursing Care
- General Assessment
- Neurological Pre-operative Assessment
General Assessment in NTDs
Neurological Pre-Operative Assessment in NTDs
Check Mamdouh Notes
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