L3: Pathogenesis Flashcards
1
Q
what effects the likelihood & severity of parasitic diseases
A
- The status of host defenses
- The number of parasites present
- Parasite pathogenicity
2
Q
what is hemozoin and what produces it
A
- hemozoin = crystallized dimers of heme that impair phagocytic function
- Plasmodium (malaria) parasites digest hemoglobin and produce hemozoin
- macrophages ingest hemozoin and infected RBCs