L3: Pathogenesis Flashcards

1
Q

what effects the likelihood & severity of parasitic diseases

A
  • The status of host defenses
  • The number of parasites present
  • Parasite pathogenicity
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2
Q

what is hemozoin and what produces it

A
  • hemozoin = crystallized dimers of heme that impair phagocytic function
  • Plasmodium (malaria) parasites digest hemoglobin and produce hemozoin
  • macrophages ingest hemozoin and infected RBCs
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