L3 - Development of the GI Tract and GI Organs II Flashcards

Feb. 6, 2019

1
Q

What empties into the cloaca?

A

GU and GI tracts

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2
Q

What causes a volvulus most of the time?

A

Lack of fibrous tissue connecting it to adjacent structures so the gut is free to move and twist

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3
Q

What causes the stenotic segment in Hirschsprung disease?

A

absence of autonomic innervation of segment of intestine

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4
Q

What is the lower anal canal?

A

proctodeum

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5
Q

In a reversed rotation of the gut, where does the duodenum lie?

A

Anterior to the transverse colon

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6
Q

What are the symptoms associated with non-rotation of the gut?

A

Generally asymptomatic

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7
Q

Where does the ectoderm meet the endoderm in the GI tract?

A

pectinate line

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8
Q

Where does the cecum stand after 180 degrees of rotation?

A

In a subhepatic position

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9
Q

Where does the cecum lie in a mixed rotation/volvulus?

A

Inferior to the pylorus but fixed to the posterior wall by peritoneal bands

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10
Q

What side of the cecum does the appendix grow from?

A

Posterior medial side

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11
Q

The hindgut gets arterial supply from? It drains into? Where does lymph go?

A

Inferior mesenteric artery, inferior mesenteric vein, inferior mesenteric lymph nodes

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12
Q

What complication can occur with a subhepatic cecum?

A

Difficulty with diagnosing appendicitis versus cholecystitis

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13
Q

Patency of the omphaloenteric duct with the outer abdominal wall is called what?

A

Umbilical fistula

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14
Q

What is the difference between an omphalocele, umbilical hernia, and gastroschisis?

A

Omphalocele is surrounded by fetal membranes, while an umbilical hernia is covered by skin. Both herniate out through the umbilicus, but gastroschisis usually occurs lateral to the medial plane

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15
Q

What muscle defines low from high anorectal abnormalities?

A

puborectalis

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16
Q

What are the “twos” of Meckel’s diverticulum?

A

1) two feet proximal to the ileocecal junction
2) occurs in 2% of the population
3) approximately two inches long
4) contains two types of tissue: pancreatic and gastric
5) symptoms present before two years of age
6) male to female ratio is 2 to 1

17
Q

Above the pectinate line, what is the blood supply? Below?

A

Above: superior rectal artery of the inferior mesenteric artery
Below: inferior rectal artery of the internal pudendal

18
Q

Duodenal atresia and Hirschsprung disease are associated with which disorder?

A

Down Syndrome

19
Q

What separates high anorectal abnormalities from low ones superficially?

A

High anorectal abnormalities have no pigmentation/dimple at anus and have a flat perineum

20
Q

What is a complication of reversed rotation?

A

Compression of the transverse colon by the SMA

21
Q

What causes anal stenosis?

A

Slight dorsal deviation of the urorectal septum

22
Q

Above the pectinate line, what is the innervation? Below?

A

Above: autonomics
Below: pudendal nerve

23
Q

Why might a Meckel’s diverticulum be prone to an ulcer?

A

Contains gastric tissue which can corrode the intestinal lining

24
Q

Where is the large intestine found in non-rotation of the gut?

A

On the left side of the body

25
Q

What causes a vitelline cyst?

A

Persistence of the omphaloenteric duct which continues secreting leading to cysts

26
Q

What causes membranous atresia?

A

failure of the epithelial plug to perforate at the end of the eighth week

27
Q

What are some defining characteristics of low anorectal abnormalities?

A

1) no anal canal
2) anal bulge
3) anal dimple or stenotic opening or abnormal opening in perineum

28
Q

What is the embryological defect that causes Hirschsprung?

A

failure of neural crest cell migration

29
Q

Which limb of the midgut grows faster?

A

Cranial limb grows faster than caudal limb

30
Q

What axis does the midgut rotate around?

A

SMA

31
Q

Why might a cecum be subhepatic?

A

Cecum may adhere to the liver not allowing it to descend into the iliac fossa

32
Q

What partitions the cloaca?

A

urorectal septum

33
Q

What is the definition of a volvulus?

A

Twisting of the intestines, usually the cause of an obstruction