L3: cardiovascular disease/ HTN Flashcards
BLOOD PRESSURE CATEGORIES :
normal : less than 120/80
elevated:
120-129/less than 80
stage 1 hypertension:
130-139/80-89
stage 2 hypertension :
>140/>90
hypertensive crisis:
>180/>120
systolic BP is more important cardiovascular risk factor when ?
after age of 50 . before then it is the diastolic which is more important
what’s the difference between a hypertensive urgency and a hypertensive emergency ?
hypertensive urgency : severely elevated BP no progressive organ dysfunction , usually due to uncontrolled HTN
Hypertensive emergency :
severely elevated BP with end organ dysfunction
examples of hypertensive emergencies :
Hypertensive encephalopathy
Acute left ventricular failure with pulmonary edema
Acute MI or unstable angina pectoris
Dissecting aortic aneurysm
essential hypertension means _____
HTN with no known etiology , 95% of cases
causes of secondary HTN :
intrinsic renal disease
renovascular disease
mineralocorticoid excess
sleep breathing
disorders
chronic steroid therapy
uncommon (just read):
Pheochromocytoma
Glucocorticoid excess
Coarctation of Aorta
Hyper/hypothyroidism
increased creatine and abnormal urinalysis (renovascular and renal parenchymal disease is a clue to
secondary HTN
SO IS episodic headache , chest pain , palpitations , morbid obesity ,unexplained hypokalemia (hyperaldersteronisim)
impaired blood glucose (hypercortisolism)
impaired TFT (hypo/hyper thyroidism)
complications of prolonged uncontrolled HTN :
change in vessel wall leading to injury and arteriosclerosis throughout vasculature
target organ dysfunction
target organs of HTN ;
CVS ( heart and vessels):
-left ventricular hypertrophy
-angina or prior myocardial infarction
-prior coronary revascularization
-heart failure
-peripheral arterial disease
kidneys:
-chronic kidney disease
nervous system:
-stroke or transient ischemic attack
eyes:
-retinopathy
cardiovascular risk factors of HTN( not obvious ):
microalbuminuria
routine lab tests:
-EKG
-CXR
-urinalysis
-blood glucose and hemocrit
-serum potassium , -creatine(GFR) and calcium
-lipid profile
-Urinary albumin excretion
treatment goal of HTN in otherwise healthy patient :
<140/90
primary goal is attaining the systolic blood pressure
treatment goal of HTN in patient suffering from diabetes:
<130/80
\
primary goal is attaining the systolic blood pressure