L12: Amoebiasis

Question 1

which intestinal amoebiasis causes amoebiasis?

Answer 1

Entamoeba histolytica (invasive strain giving rise to fecal cysts )

non invasive strain : E.dispar

Question 2

-resistant yo chlorine in normal conc.

-killed by freezing or heating (55%)

-very long period of communicability

Question 3

modes of transportation :

Answer 3

feco-oral route

agency of cockroaches , flies or rats

Question 4

incubation period :

Answer 4

2-4 weeks

Question 5

most common type of amoebic infection :

Answer 5

asymptomatic cyst passage

Question 6

clinical presentation of intestinal amoebiasis :

Answer 6

-abdominal cramps
-mild diarrheia to colitis and dysentery
-fulminant colitis
-mucus in stool
-flask shaped ulcer in intestine

Question 7

extra intestinal amoebiasis clinical presentations :

Answer 7

-amoebic liver abscess(most common extra-intestinal complication)
-rarely , lungs , skin , and genitalia and CNS are affected. spleen and pericardium too

-can cause jaundice as well but it is rare, pleural effusion is more common

Question 8

inflammatory and edematous reaction around trophozoites :

Answer 8

amoeboma

Question 9

90% of patinets are asymptomatic carriers

Question 10

chronic form of amoebic colitis that’s characterized by intestinal bleeding , perforation , paralytic ileus , and high fever :

Answer 10

fulminant colitis
-can be confused with inflammatory bowel disease

Question 11

amoeboma :

Answer 11

-pseudotumoral lesion
-necrosis , edema , and inflammatory thickening of mucosa and submucosa of intestinal wall
-palpable mass of trophozites
-always coexists with ulceration
-single, rarely multiple :in different sites of colon , on skin , at site of amoebic liver aspiration

Question 12

which lobe of the liver harbors abscesses more commonly ?

Answer 12

the right lobe

-abscess of the left lobe is more dangerous due to its proximity with the heart —> rupture—.pericardial effusion

Question 13

treatment :

Answer 13

tinidazole